MDCT Pulmonary Angiography Evaluation of Pulmonary Embolism in Children

Kritsaneepaiboon, Supika; Lee, Edward Y.; Zurakowski, David; Strauss, Keith J.; Boiselle, Phillip M.

doi:10.2214/ajr.08.1299

Cited by 65 publications

(44 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…1). Kritsaneepaiboon et al [4] found a lower lobe predilection (right lower lung lobe>left lower lung lobe) of pulmonary embolism in children, as seen in adults. Thus, detailed assessment of pulmonary arteries in both lower lung lobes should be emphasized in routine clinical practice.…”

Section: Ct Findings Of Acute Pulmonary Embolismmentioning

confidence: 99%

“…Studies have shown a high diagnostic performance of multidetector CT pulmonary angiography for pulmonary embolism detection in children [3, 4]. Compared with central pulmonary emboli, identification of peripheral (subsegmental) pulmonary embolism in children is more difficult due to the small size of pulmonary vessels of children.…”

Section: Ct Findings Of Acute Pulmonary Embolismmentioning

confidence: 99%

“…Recent studies reported radiation doses of children undergoing CT pulmonary angiography ranged from 2 to 26 mSv. Importantly, there is no added radiation dose with dual-energy CT compared to CT pulmonary angiography [4, 12, 34, 56]. For example, Zhang et al [34] reported the mean effective radiation dose from dual-energy CT pulmonary angiography was 2.3±1.1 mSv (range: 1.1 to 7.1 mSv) in 32 children with nephrotic syndrome, which was comparable to or lower than effective dose reported in previous studies using single-source, single-energy CT pulmonary angiography.…”

Section: Radiation Dose Considerationmentioning

confidence: 99%

“…For example, Zhang et al [34] reported the mean effective radiation dose from dual-energy CT pulmonary angiography was 2.3±1.1 mSv (range: 1.1 to 7.1 mSv) in 32 children with nephrotic syndrome, which was comparable to or lower than effective dose reported in previous studies using single-source, single-energy CT pulmonary angiography. Victoria et al [3] reported that the mean effective dose was 2–5 mSv, while Kritsaneepaiboon et al [4] reported mean effective dose as 10.5 mSv (range: 2.3–26 mSv). The range of radiation doses in children undergoing CT pulmonary angiography stems from the varying CT equipment and the scanning parameters at different centers.…”

Section: Radiation Dose Considerationmentioning

confidence: 99%

“…It is traditionally believed that the incidence of pulmonary embolism is much lower in children than in adults. However, recent studies using CT pulmonary angiography have demonstrated a high incidence (14–15.5%) of pulmonary embolism in children when there is clinical suspicion of such disease [3, 4]. In children with nephrotic syndrome, the frequency of pulmonary embolism was reported to be up to 17% [5].…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Multidetector computed tomography pulmonary angiography in childhood acute pulmonary embolism

et al. 2015

View full text Add to dashboard Cite

Pulmonary embolism is a life-threatening condition affecting people of all ages. Multidetector row CT pulmonary angiography has improved the imaging of pulmonary embolism in both adults and children and is now regarded as the routine modality for detection of pulmonary embolism. Advanced CT pulmonary angiography techniques developed in recent years, such as dual-energy CT, have been applied as a one-stop modality for pulmonary embolism diagnosis in children, as they can simultaneously provide anatomical and functional information. We discuss CT pulmonary angiography techniques, common and uncommon findings of pulmonary embolism in both conventional and dual-energy CT pulmonary angiography, and radiation dose considerations.

show abstract

Section: Ct Findings Of Acute Pulmonary Embolismmentioning

confidence: 99%

Section: Ct Findings Of Acute Pulmonary Embolismmentioning

confidence: 99%

Section: Radiation Dose Considerationmentioning

confidence: 99%

Section: Radiation Dose Considerationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Multidetector computed tomography pulmonary angiography in childhood acute pulmonary embolism

et al. 2015

View full text Add to dashboard Cite

show abstract

The utility of risk assessment tools for acute pulmonary embolism in children

Ergenekon

Yeğit

Cenk

et al. 2022

Pediatric Pulmonology

View full text Add to dashboard Cite

Background and Aim: Pulmonary embolism (PE) is a potentially life-threatening disease in children. The objective of the study is to evaluate the utility of adult-based pulmonary embolism rule-out criteria (PERC), Pediatric PE Model, and D-dimer in the diagnosis of PE in children. Material and Methods: The study consisted of patients under 18 years of age who were consulted to the Pediatric Pulmonology Clinic for the evaluation of PE. Patients were divided into two groups based on the confirmation of PE. The group with the presence of PE (n = 20) consisted of children who were diagnosed with PE. The group with the absence of PE (n = 28) consisted of children with clinically suspected PE but negative diagnostic imaging. Adult validated clinical decision PERC rule and Pediatric PE Model were retrospectively applied to the patients.Results: In the study, PERC demonstrated a sensitivity of 60% and a specificity of 46% for the diagnosis of PE in children. When PE Model was evaluated for the children, it was found a 50% sensitivity and 75% specificity. Combining PE Model and PERC rule with D-dimer did not increase the specificity and sensitivity. Smoking was found to be relevant for PE in the childhood. Twenty-five percent of the patients had a genetic tendency for PE. All of the patients had an underlying disease as well.Conclusion: None of the current risk assessment tools (PE Model, PERC, D-dimer) were found to be accurate in predicting PE. Further larger population studies are still required to develop a better diagnostic approach.

show abstract