MCM4 expression is associated with high-grade histology, tumor progression and poor prognosis in urothelial carcinoma
Go Kobayashi,
Tetsutaro Hayashi,
Kazuhiro Sentani
et al.
Abstract:Background
We previously reported Minichromosome maintenance 4 (MCM4) overexpression in gastric cancer. However, the clinicopathological significance of MCM4 in urothelial carcinoma (UC) has not been investigated. To clarify the clinicopathological significance of MCM4 in UC, we investigated MCM4 expression with immunohistochemistry (IHC).
Methods
We analyzed the expression and distribution of MCM4 in 124 upper tract urothelial carcinoma (UTUC) sam… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.