“…The second primary molars are of the utmost importance in the occlusion, since they have an eruption guide for the eruption of the first permanent molars [16,21]. Several effects of premature space loss are mentioned, such as dental crowding, ectopic eruption, impaction of the permanent tooth, crossbite, center line discrepancies, and, in cases of premature loss of deciduous second molars, tipping of the first permanent molar can occur [16,[22][23][24][25]. Therefore, it is essential to maintain the second primary molar until the first permanent molar tooth and the successor erupt successfully.…”