In this paper, we give the definition of local variable Morrey-Lorentz spaces M loc p(•),q(•),λ (R n ) which are a new class of functions. Also, we prove the boundedness of the Hardy-Littlewood maximal operator M and Calderón-Zygmund operators T on these spaces including the class of sublinear operators T 0 generated by Calderón-Zygmund operators. Finally, we apply these results to the Bochner-Riesz operator B δ r , identity approximation A ε and the Marcinkiewicz operator µ Ω on the spaces M loc p(•),q(•),λ (R n ).