Maximal inspiratory pressure is associated with health-related quality of life and is a reliable method for evaluation of patients on hemodialysis

Vieira, Carlos Filipe Delmondes; Costa, Henrique Silveira; Lima, Márcia Maria Oliveira; Alves, Frederico Lopes; Rodrigues, Vanessa; Maciel, Emílio Henrique Barroso; Prates, Maria Cecília Sales Mendes; Lima, Vanessa Pereira de; Mendonça, Vanessa Amaral; Lacerda, Ana Cristina Rodrigues; Figueiredo, Pedro Henrique Scheidt

doi:10.1080/09593985.2020.1818338

Cited by 2 publications

(4 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the MS setting, we can, however, put our findings in perspective with the results of clinical trials on individuals with MS, which have reported changes in respiratory muscle strength 41 those with chronic stable heart failure (11.4 cmH 2 O), 42 and those on hemodialysis (13.8 cmH 2 O). 32 These values barely differ from our results; however, the discrepancies observed between these studies could lie in the type of population in each study. Ninety-five percent of individuals with stable disease will have change scores lower than the MDC; therefore, a change greater than this value is not likely to occur in a stable patient.…”

Section: Discussioncontrasting

confidence: 96%

“…To our knowledge, no other study has demonstrated the ICCs of respiratory muscle strength measures in individuals with MS. However, the ICCs found in our study are consistent and even higher than those had in the literature for other populations 32-35. This finding suggests that changes in respiratory muscle strength in individuals with MS who undergo a respiratory muscle training program are genuinely due to the intervention and are not an artifact of the test, which could mask the true effects of the intervention and have serious ramifications on the conclusions.…”

Section: Discussionsupporting

confidence: 90%

“…Following the same argument proposed earlier, we compared the changes observed after an inspiratory muscle training intervention based on the percentage of predicted value in individuals with MS. Two clinical trials36,40 obtained a change of over 35% for MIP, which exceeds our current MDC. These findings are supported by other conditions that showed similar MDC values for MIP in individuals with chronic obstructive pulmonary disease (13 cmH 2 O),41 those with chronic stable heart failure (11.4 cmH 2 O),42 and those on hemodialysis (13.8 cmH 2 O) 32. These values barely differ from our results; however, the discrepancies observed between these studies could lie in the type of population in each study.…”

Section: Discussionsupporting

confidence: 87%

“…However, the ICCs found in our study are consistent and even higher than those had in the literature for other populations. [32][33][34][35] This finding suggests that changes in respiratory muscle strength in individuals with MS who undergo a respiratory muscle training program are genuinely due to the intervention and are not an artifact of the test, which could mask the true effects of the intervention and have serious ramifications on the conclusions. This is the first study to determine the MDCs for respiratory muscle strength measures in individuals with MS.…”

Section: Discussionmentioning

confidence: 81%

See 3 more Smart Citations

Reliability and Minimal Detectable Change for Respiratory Muscle Strength Measures in Individuals With Multiple Sclerosis

Aguilar-Zafra,

Fabero-Garrido,

del Corral

et al. 2023

Journal of Neurologic Physical Therapy

View full text Add to dashboard Cite

Background and Purpose: The test-retest reliability and minimal detectable changes (MDCs) for respiratory muscle strength measures have not been determined in individuals with multiple sclerosis (MS). This study determined the test-retest reliability and MDCs for specific respiratory muscle strength measures, as well as their associations with health-related quality of life (HRQoL), disability, dyspnea, and physical activity level measures in this population. In addition, the study examined differences in respiratory muscle strength between different degrees of disability. Methods: Sixty-one individuals with MS attended 2 appointments separated by 7 to 10 days. Respiratory muscle strength was evaluated by maximal inspiratory and expiratory pressures (MIP/MEP), HRQoL by EuroQol-5D-5L (index and visual analog scale [EQ-VAS]), disability by the Expanded Disability Status Scale, dyspnea by the Medical Research Council scale, and physical activity levels by the International Physical Activity Questionnaire. Results: Respiratory muscle strength measures had excellent test-retest reliability (ICC ≥ 0.92). The MDC for MIP is 15.42 cmH2O and for MEP is 17.84 cmH2O. Participants with higher respiratory muscle strength (MIP/MEP cmH2O and percentage of predicted values) had higher HRQoL (r = 0.54-0.62, P < 0.01, EQ-5D-5L index; r = 0.30-0.42, P < 0.05, EQ-VAS); those with higher expiratory muscle strength (cmH2O and percentage of predicted values) had lower levels of disability (r ≤ −0.66) and dyspnea (r ≤ −0.61). There were differences in respiratory muscle strength between different degrees of disability (P < 0.01; d ≥ 0.73). Discussion and Conclusion: Respiratory muscle strength measures provide excellent test-retest reliability in individuals with MS. MDCs can be interpreted and applied in the clinical setting. Low respiratory muscle strength can contribute to a poor HRQoL; specifically, expiratory muscle strength appears to have the strongest influence on disability status and dyspnea. Video Abstract available for more insights from the authors (see the Video, Supplemental Digital Content 1, available at: http://links.lww.com/JNPT/A455).

show abstract

Section: Discussioncontrasting

confidence: 96%

Section: Discussionsupporting

confidence: 90%