Maxillary undifferentiated high-grade pleomorphic sarcoma: A case report and review of the literature

Abstract

Undifferentiated high-grade pleomorphic sarcoma is a tumor of mesenchymal cells without clear cell differentiation and represents a diagnosis of exclusion. It is located mainly in extremities, so its location in the head and neck is extremely rare. We report the case of an undifferentiated high-grade pleomorphic sarcoma located on the hard palate.

Undifferentiated pleomorphic sarcoma of the floor of mouth: A rare case

“…[ 11 ] Its location in the head and neck is rare. [ 12 ] The most frequent location in head and neck is the neck and parotid gland, followed by the scalp, face, anterior skull base, and orbit. Their presence in oral cavity is extremely rare.…”

“…Clinically, the most common symptom is the presence of a mass of progressive and rapid growth that may be associated with nonspecific symptoms such as pain and paresthesia of the compromised site. [ 12 ] Imaging studies like the computed tomography and magnetic resonance imaging usually reveal a heterogeneously enhancing, lobulated soft tissue mass with adjacent soft tissue, and bone extension. The gross appearance is typically heterogeneous with areas of gelatinous firm and fleshy components admixed with areas of necrosis and cystic hemorrhagic change.…”