Maxillary Sinus Mucosal Blood Flow During Nasal vs Tracheal Respiration

Nasal Obstruction: An Alternative to Ostiomeatal Complex Dysfunction in Sinus Disease

“…Salman 10 documented the absence of clinical sinusitis despite radiological and endoscopic demonstration of OMC dysfunction and, conversely, the continued occurrence of sinusitis despite adequate corrective surgery. Recent work in our laboratory also suggests that factors other than ostial occlusion and OMC dysfunction, notably, lack of stimulation of flow receptors in the nasal cavity secondary to deprivation of nasal airflow and a subsequent decrease in antral blood perfusion, might play an essential role in the pathophysiology of sinusitis 11,12 . Our hypothesis relating nasal obstruction to sinus disease, independent of ostial obstruction and antral hypoventilation, remains to be tested experimentally.…”

Holes in the head: Evolutionary interpretations of the paranasal sinuses in catarrhines

“…155 That is, they assume, explicitly or otherwise, that sinuses must do something. 72 There is, however, an alternative view: It may be that the bony sinus itself is a red herring, and that the process of bone resorption is the "function" in question. In this scheme, dubbed the transgression-regression model of passive pneumatization, 156 the sinus itself is a functionless remnant of osteoclastic activity in the cranium.…”

“…73,78 In other mammals, there is a significant relationship between nasal respiration and maxillary sinus blood flow. 72,83 Experimental data show that venous blood flow in the paranasal sinuses is an important mechanism for the prevention of pneumatic cavity infections. 72,73 In fact, an acute bacterial infection of the paranasal sinuses is usually accompanied by an increase of blood flow in the paranasal sinuses.…”

“…72,83 Experimental data show that venous blood flow in the paranasal sinuses is an important mechanism for the prevention of pneumatic cavity infections. 72,73 In fact, an acute bacterial infection of the paranasal sinuses is usually accompanied by an increase of blood flow in the paranasal sinuses. Curiously, however, this mechanism does not work in the case of chronic inflammation.…”

Anatomía comparada de los senos frontales en el félido dientes de sable primitivo <i>Promegantereon ogygia</i> (Felidae, Machairodontinae) y felinos actuales de tamaño similar

“…Several hypotheses have been proposed to explain the function of these cranial pneumatisation, most of them related to physiology or architecture, development and biomechanics of the skull, such as: imparting resonance to the voice (Cleland, 1862;Bignon, 1889;Leakey & Walker, 1997;Dyce et al, 2002), protection of the brain from shocks (Rui et al, 1960;Schaffer & Reed, 1972;Davis et al, 1996), reducing cranial weight (Cleland, 1862;Paulli, 1900;Nemours, 1931;Shea, 1936;Buhler, 1972;Davis et al, 1996), increasing surface area of olfactory mucosa (Braune & Clasen, 1877;Negus, 1957Negus, , 1958, humidifying and warming the inspired air (Proetz, 1922(Proetz, , 1938O'Malley, 1924;Gannon et al, 1997), thermoregulation of the brain (Bignon, 1889;Bremer, 1940;Proetz, 1953;Verheyen, 1953;Dyce et al, 2002), or producing nitric oxide gas (Lundberg et al, 1994). Nevertheless, no one of these hypotheses is completely satisfactory or widely applicable.…”