Maxillary Sinus Mucopyocele in a Fifty-Eight-Year-Old man: A Possible Late Complication of Irradiation to Head and Neck

Abstract

Introduction:A mucocele is an epithelial-lined, mucus-containing sac that can fill the sinus completely and expand gradually. Mucopyocele is an infected mucocele.Case Report:We presented a case of left maxillary mucopyocele in a 58-year-old man that developed after radiotherapy for nasopharyngeal carcinoma. Computed tomography scan showed opacification of the left maxillary sinus expanding through the medial wall of the antrum with thinning and destruction of the adjacent structures. Endoscopic marsupialization of the lesion and left partial maxillectomy were performed. The cystic mass had yellowish thick mucopurulent fluid that was completely drained.Conclusions:A few cases of sphenoid sinus mucocele as a late complication of radiation therapy have been reported. Maxillary mucocele and mucopyocele can be considered as one of the late complications of radiotherapy to head and neck as a result of occlusion of sinus ostia by scarred mucosa.

Radiation-Related Superficial Oral Mucoceles: an Under-Recognized Acute Toxicity in Head and Neck Cancer Patients

“…Possibly, this is the first evidence of SOMs during the course of HNRT, which were recognized early because all patients included in this study were submitted to systematic oral evaluations throughout the course of HNRT, which is part of the oral care treatment protocols of our service. SOM can present as single or multiple mucosae vesicles and often present as "short-lived lesions" because they frequently rupture and cause superficial painful ulcers (5,6,8). In the current case series, none of the patients reported SOM-associated pain and they were all unaware of the existence of these lesions.…”

“…Remarkably, there is still a lack of information regarding oral toxicities that might occur during cancer therapy in HNSCC patients (3). Of note, conventional mucoceles were previously described in different anatomic sites of patients who concluded HNRT, including the maxillary sinus (5,6); the sphenoidal sinus (7)(8)(9)(10); and the ethmoidal sinus (10,11). Therefore, the aim of this study was to describe an original case series of HNSCC patients who developed superficial oral mucoceles (SOM) during HNRT.…”

Post-Radiation Sphenoidal Mucocele in a Patient Treated for Nasopharyngeal Cancer

“…Irradiation for nasopharyngeal carcinoma and sphenoidal seat are the most frequently reported. 2,5,[7][8][9] Radiotherapy can cause obstruction of the sinus ostium by induced fibrosis. 5,7,8 Mucoceles can cause various signs and symptoms, depending on the affected area; those symptoms can be rhinological, ophthalmic or neurological.…”

Radiation-related superficial oral mucoceles: An under-recognized acute toxicity in head and neck cancer patients

“…SOM can present as single or multiple mucosae vesicles and often present as “short-lived lesions” because they frequently rupture and cause superficial painful ulcers ( 5 , 6 , 8 ). In the current case series, none of the patients reported SOM-associated pain and they were all unaware of the existence of these lesions.…”

“…Of note, conventional mucoceles were previously described in different anatomic sites of patients who concluded HNRT, including the maxillary sinus ( 5 , 6 ); the sphenoidal sinus ( 7 - 10 ); and the ethmoidal sinus ( 10 , 11 ). Therefore, the aim of this study was to describe an original case series of HNSCC patients who developed superficial oral mucoceles (SOM) during HNRT.…”