Maxillary giant cell tumor (GCT) is a rare benign bone lesion. It usually appears in the long bones. However, in the head and neck region GCT could also occur although the frequency is only 2% of the all GCT cases. We present a case of a 20-year-old female with GCT of left maxillary sinus who underwent complete resection via subtotal maxillectomy with Weber Ferguson approach. This technique provides wider visual field operation to taken out the whole tumor. To cover the defect of the palatal authors put an obturator. After three months followed up, there were no signs of recurrence with excellent aesthetic result.