Maxillary necrosis by Mucormycosis: A Case Report

Abstract

A 50-year-old woman with type 2 diabetes was referred to the hospital with a 4-week history of a facial redness that proceeded to significant midface ulceration and bilateral vision loss. Her nasal bridge was completely collapsed, she had naso-palatal ulceration with black eschars on the mucosa, and her fasting blood sugar was significantly increased. Her blood sugar was controlled with soluble insulin through sliding scale, and surgical debridement was performed, which revealed fungal hyphae on histo-pathological assessment. Ketoconazole, an antifungal drug, was commenced immediately. She progressed slowly but steadily after that and her wound became clear with fresh granulation tissue. Keywords: Mucormycosis, Uncontrolled diabetic mellitus

Oral Manifestations of Mucormycosis: A Systematic Review

“…Only [25,27,[32][33][34]. Thus, as seen in most cases, dental history generally plays a vital role in the development of rhinocerebral mucormycosis, which can increase susceptibility to its progression.…”

“…Only cases published by Ramadorai et al, Srivastava et al Ramesh et al, Verma et al, and Anwar et al had no dental history highlighted [ 25 , 27 , 32 , 33 , 34 ]. Thus, as seen in most cases, dental history generally plays a vital role in the development of rhinocerebral mucormycosis, which can increase susceptibility to its progression.…”

“…Thus, as mentioned by Anwar et al, diabetes interferes with the body’s immune response to infection. A high glycemic index increases fungal proliferation and reduces chemotaxis and phagocytic efficacy [ 34 ].…”