Maturity Assessment and Curve Progression in Girls with Idiopathic Scoliosis

Abstract

The curve-acceleration phase separates curves into various types of curve progression. The Tanner-Whitehouse-III RUS scores are highly correlated with timing relative to the curve-acceleration phase and provide better maturity determination and prognosis determination during adolescence than the other parameters tested. Accurate skeletal maturity determination should be used as the primary maturity measurement in girls with idiopathic scoliosis.

Participation of sex hormones in multifactorial pathogenesis of adolescent idiopathic scoliosis

“…8 Mean concentration of RANKL in the groups of girls studied for bone formation to assess osteoblastic activity. Both markers are increased in metabolic bone diseases with increased bone or osteoid formation including osteopenia, osteoporosis, as well as in adolescent idiopathic scoliosis [39][40][41][42][43][44].…”

Abnormal anthropometric measurements and growth pattern in male adolescent idiopathic scoliosis

“…However, the results of several other studies have identified chronological age as a variable that predicts skeletal maturity and curve progression in AIS [16,18,22]. During the subsequent study of the growth patterns of male AIS subjects, several other parameters could be used to reflect maturity, including the Risser sign [2,20,29,36], the digital skeletal age (DSA) [27,28] and Tanner's pubertal stages [30]. Second, as in any other cross-sectional study, no definitive conclusion concerning the evolution of the anthropometric parameters over time can be drawn.…”

Brace Management in Adolescent Idiopathic Scoliosis

“…Tanner staging, although quite familiar to pediatricians, is often not accurately gauged by orthopaedic surgeons. Girls typically reach peak height velocity (PHV), the maximum increase in growth rate during the adolescent growth spurt, 18 to 24 months earlier than boys, typically between Tanner stages 2 and 3, whereas boys do so between stages 3 and 5 [45][46][47]. This phase of growth represents a period of increased risk of curve progression.…”

“…Sanders et al [47] used Tanner-Whitehouse-III staging on hand radiographs to predict the period of rapid curve progression (curve acceleration phase [''CAP'']). Their findings are interesting, because they demonstrated patients who are Risser 0 may have different estimated CAP scores, which resulted in substantially different rates of progression.…”