Mature embryoid teratoma in the wall of a mucinous cyst adenoma of ovary in multiparous female

Naim, Mohammed; Haider, Nazima; John, Vanesa T; Hakim, Seema

doi:10.1136/bcr.07.2010.3205

Cited by 6 publications

(4 citation statements)

References 6 publications

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“…Accounting for the presence of malignant tumors with mature teratomas, 10 cases of ovarian carcinoma are reported, one case of adenomatoid tumor, and one case of fibrothecoma, which are occasionally malignant [13,[30][31][32][33][34][35][36][37][38][39][40]. Of our patients, one had endometrioid cancer, and one had borderline cancer.…”

Section: Discussionmentioning

confidence: 99%

Co-existence of Ovarian Teratomas With Other Gynecological Tumors

Matalliotakis,

Matalliotaki,

Tsakiridis

et al. 2024

Cureus

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Introduction: This study aims to investigate the co-existence of ovarian teratomas with other benign or malignant gynecological tumors in women who underwent gynecological surgery.Methods: We retrospectively reviewed all women who underwent gynecological surgery over a 15-year period. Pre-operative, surgical, and histological records were obtained from women who presented with gynecological pathology, aiming to discover a possible link between ovarian teratomas and other gynecological tumors.Results: Of the total patient sample, 288 (8.2%) had a mature teratoma, and 9 (0.3%) had an immature teratoma. The mean age was 38.0±13.3 years and 30.9±11.1 years, respectively. Women with mature teratoma showed a positive correlation with struma ovarii (SO, p=0.001). Moreover, we reported a positive linear relationship between struma ovarri and thecoma. Of the 288 women with a mature teratoma, 1 (0.3%) had co-existent endometrioid ovarian cancer, and 1 (0.3%) had borderline cancer. There were 14 women (4.9%) with a co-existent serous cystadenoma, 7 (2.4%) with a mucin cystadenoma, 1 (0.3%) with a thecoma, 4 (1.4%) with struma ovarii, 3 (1.0%) had Brenner cyst, 3 (1.0%) had ovarian fibroma, 2 had endometriosis (0.7%), and 8 (2.8%) had endometriomas. Of a total of nine women with immature teratomas, one (11.1%) had a serous cystadenoma.Conclusions: Ovarian teratomas may co-exist with other gynecological diseases. Our study reports various cases of the co-existence of several gynecological tumors with teratomas.

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Section: Discussionmentioning

confidence: 99%

Co-existence of Ovarian Teratomas With Other Gynecological Tumors

Matalliotakis,

Matalliotaki,

Tsakiridis

et al. 2024

Cureus

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“…To our knowledge, there have been 25 reports on 45 ovarian collision tumors in English language literature, 1–6,9–25 since YM Bhende reported a Brenner tumor in the wall of a serous cystadenoma in 1947 9 . The histological findings were described for all 45 ovarian collision tumors, with 14 combinations of teratomas and cystadenomas, 9 teratomas and cystadenocarcinomas, 12 cystadenomas/cystadenocarcinomas and other tumors, 6 teratomas and other tumors, and 4 other extremely rare combinations 4,10–12 .…”

Section: Discussionmentioning

confidence: 99%

Ultrasound Findings andO‐RADSMalignancy Risk Stratification of Ovarian Collision Tumors

Guo

Zhou

Zhao

et al. 2021

J of Ultrasound Medicine

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Objectives-To describe the ultrasonographic signs of ovarian collision tumors and evaluate the malignancy risk using the O-RADS system.Methods-This was a retrospective analysis of 25 ovarian collision tumors from 8739 patients between May 2010 and January 2020. All clinical characteristics, ultrasound images, and histological findings were collected and analyzed. Using the O-RADS lexicon descriptors, the O-RADS score was determined by two senior doctors. Lesions with O-RADS scores of 1 to 3 were classified as benign tumors, and lesions with O-RADS scores of 4 to 5 were classified as malignant tumors.Results-The mean age of the 25 patients was 30.4 years. Histological findings showed that all tumors were a combination of mature cystic teratomas and cystadenomas/cystadenocarcinomas. There were 11 benign tumors of O-RADS 2 or 3, including 3 uniocular cysts, 3 dermoid cysts, and 5 dermoid cysts with an anechoic fluid cavity. There were 12 benign tumors of O-RADS 4, including 3 uniocular-multilocular cysts with solid components, 2 multilocular cysts with irregular walls, and 8 multilocular cysts with dermoid sacs. One borderline tumor of O-RADS 4 was a multilocular cyst with irregular septation. One malignant tumor of O-RADS 5 was a multilocular cystic tumor with solid components and ascites.Conclusions-The most common ovarian collision tumor was the coexistence of a mature cystic teratoma and a cystadenoma. The O-RADS system was able to sensitively detect malignant tumors in this series. A typical dermoid cyst with an anechoic cavity or a multilocular cyst with a dermoid sac may signify a benign collision tumor.

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“…This last hypothesis is referring to the coexistence of two tumors within one tumor, also cited as a “collision tumor” by other authors [11]. One case report described the growth of a mature teratoma within a large mucinous cystadenoma, and attributed the development of the teratoma to either epithelial metaplasia of the lining of the cystadenoma or from cell rests within the neoplasm [12].…”

Section: Discussionmentioning

confidence: 99%

Benign Ovarian Tumors in Pregnancy: A Case Report of Metachronous Ipsilateral Recurrent Mucinous Cystadenoma in Initial Pregnancy and Mature Cystic Teratoma in Subsequent Pregnancy

Schreck

Mikdachi

2019

Cureus

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Mucinous cystadenomas of the ovary are benign epithelial neoplasms that can grow rapidly during pregnancy. They may cause ovarian torsion, virilization, inferior vena cava syndrome, and even preterm labor and fetal growth restriction. Various theories exist regarding the pathogenesis of these tumors. One hypothesis suggests that they may arise from teratomas. Our case report describes synchronous mucinous cystadenomas and ovarian teratomas, as well as metachronous mucinous cystadenomas in patients with a history of ovarian teratoma. There has been no report of metachronous ipsilateral teratoma after previous mucinous cystadenoma. We present a 22-year-old female with a history of bilateral ovarian tumors in a prior pregnancy noted to have a recurrent ovarian mass on her left ovary at the time of cesarean section of a subsequent pregnancy. She had two prior cystectomies for metachronous mucinous cystadenomas of her left ovary, and a right salpingo-oophorectomy for the ovarian torsion in her previous pregnancy. On her current pregnancy, she developed a mature cystic teratoma of the remaining left ovary. The rapid growth and recurrence rate of these tumors highlights the importance of close surveillance of ovarian masses during pregnancy, even those that seem benign. In this case, a history of unilateral salpingo-oophorectomy with multiple contralateral cystectomies did not appear to affect her fertility. Her future ovarian reserve is unknown, pointing to the need for adequate pre-operative counseling in similar cases of ovarian masses in pregnancy.

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Mature embryoid teratoma in the wall of a mucinous cyst adenoma of ovary in multiparous female

Cited by 6 publications

References 6 publications

Co-existence of Ovarian Teratomas With Other Gynecological Tumors

Co-existence of Ovarian Teratomas With Other Gynecological Tumors

Ultrasound Findings andO‐RADSMalignancy Risk Stratification of Ovarian Collision Tumors

Benign Ovarian Tumors in Pregnancy: A Case Report of Metachronous Ipsilateral Recurrent Mucinous Cystadenoma in Initial Pregnancy and Mature Cystic Teratoma in Subsequent Pregnancy

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