Maturation of chikungunya virus in salivary glands of Indonesia strains of Aedes aegypti and Aedes albopictus mosquitoes: An electron microscopic study.

Abstract

Electron micrsocopic studies on the salivary glands of Aedes aegypti and Aedes albopicuts mosquitoes infected with chikungunya virus showed vacuolization in the cells of this organs and numerous chikungunya virions as crystalloid structures in intracytoplasmic area, revealing the spherical particle of 55-69 nm in diameter and the electron-dense internal structure of 41-48 nm in diameter. Virions were also found enormously in this apical cavities. No findings of virus budding from the cell surface membrane of chikungunya infected mosquito's salivary glands were obtained.