1965
DOI: 10.1016/s0140-6736(65)92903-x
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Maturation in Vitro of Human Ovarian Oocytes

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1968
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Cited by 366 publications
(130 citation statements)
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“…Early in 1965, Robert G. Edwards discovered that morphologically immature human oocytes could spontaneously mature in vitro and be subsequently fertilized [5]. Eighteen years later, the first in vitro maturation (IVM) baby came into this world [30].…”
Section: Introductionmentioning
confidence: 99%
“…Early in 1965, Robert G. Edwards discovered that morphologically immature human oocytes could spontaneously mature in vitro and be subsequently fertilized [5]. Eighteen years later, the first in vitro maturation (IVM) baby came into this world [30].…”
Section: Introductionmentioning
confidence: 99%
“…The introduction of in vitro maturation in human reproduction represented a valuable choice of protocol, when dealing with patients at risk of ovarian hyperstimulation using exogenous gonadotrophins for classical AR technologies. Since the first report of human oocyte IVM [6], the methodology has been refined and considerable progress has been achieved in terms of oocyte maturation and pregnancy rates.…”
Section: Introductionmentioning
confidence: 99%
“…Edwards (Edwards, 1965;Steptoe and Edwards, 1978). Indeed, Edwards is a giant of human ART and science in general.…”
Section: Clinical Regimens In Human In Vitro Maturationmentioning
confidence: 99%