Maturation and refinement of the maculae and foveae in the Anolis sagrei lizard

Wahle, M. Austin; Kim, Hannah Q.; Menke, Douglas B.; Lauderdale, James D.; Rasys, Ashley M.

doi:10.1016/j.exer.2023.109611

Cited by 1 publication

(2 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…During this retraction period, the retina in the incipient fovea remodels, the pit forms, and photoreceptor cells move toward the foveal centers (Figure 4B). [68,74] By hatching, the highest density of photoreceptor cells is within the lizard maculae. [74] Thus, at hatching, the retina is configured for detailed vision.…”

Section: Oriental Garden Lizardmentioning

confidence: 99%

“…[68,74] By hatching, the highest density of photoreceptor cells is within the lizard maculae. [74] Thus, at hatching, the retina is configured for detailed vision. The return to a spherical shape also likely harmonizes the refractive components to the eye's axial length, thereby providing the newborn juvenile lizards with the visual acuity necessary to be independent hunters.…”

Section: Oriental Garden Lizardmentioning

confidence: 99%

See 1 more Smart Citation

Dynamic changes in ocular shape during human development and its implications for retina fovea formation

Rasys,

Wegerski,

Trainor

et al. 2023

BioEssays

Self Cite

View full text Add to dashboard Cite

The human fovea is known for its distinctive pit‐like appearance, which results from the displacement of retinal layers superficial to the photoreceptors cells. The photoreceptors are found at high density within the foveal region but not the surrounding retina. Efforts to elucidate the mechanisms responsible for these unique features have ruled out cell death as an explanation for pit formation and changes in cell proliferation as the cause of increased photoreceptor density. These findings have led to speculation that mechanical forces acting within and on the retina during development underly the formation of foveal architecture. Here we review eye morphogenesis and retinal remodeling in human embryonic development. Our meta‐analysis of the literature suggests that fovea formation is a protracted process involving dynamic changes in ocular shape that start early and continue throughout most of human embryonic development. From these observations, we propose a new model for fovea development.

show abstract

Section: Oriental Garden Lizardmentioning

confidence: 99%