“…Of these case-control studies, for the MMP-9 -1562C>T polymorphism, 13 case-control studies in ten publications (18–28) were available, including 1396 cases and 1709 controls. For the MMP-2 -753C>T polymorphism, six case-control studies (19,21–23,27) involved a total of 693 cases and 636 controls. Among the 13 eligible studies for MMP-9 -1562C>T (rs3918242), four case-control studies (19,20,22,23) including 438 cases and 469 controls were undertaken in Caucasians (Czech and Turkey), seven case-control studies (21,24,26–28) containing 827 cases and 1144 controls were conducted in Asians (China, Taiwan, and India), and two case-control studies (18,25) with 131 cases and 92 controls was performed in Latinos populations (Brazil and Colombia).…”