Matricellular proteins: Potential biomarkers in head and neck cancer
Yunsheng Wang,
Xudong Liu,
Xingyue Wang
et al.
Abstract:The extracellular matrix (ECM) is a complex network of diverse multidomain macromolecules, including collagen, proteoglycans, and fibronectin, that significantly contribute to the mechanical properties of tissues. Matricellular proteins (MCPs), as a family of non‐structural proteins, play a crucial role in regulating various ECM functions. They exert their biological effects by interacting with matrix proteins, cell surface receptors, cytokines, and proteases. These interactions govern essential cellular proce… Show more
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