Matricaria chamomilla: A valuable insight into recent advances in medicinal uses and pharmacological activities

Joumaa, Manal M. El; Borjac, Jamilah

doi:10.1007/s11101-022-09817-0

Cited by 22 publications

(17 citation statements)

References 161 publications

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“…Particularly, potentials of oxidized bisabolene derivatives such as α-bisabolol, bisabololoxid A or bisabolonoxid stand out. Even more, polyketides of chamomile such as dicycloether derivatives reported as possible contributors to the anti-inflammatory activity (Akbaş et al, 2023;Capuzzo et al, 2014;El Joumaa & Borjac, 2022;Flemming et al, 2015;Maurya et al, 2014;Tomić et al, 2014). In this context, it can be deduced that studied samples of Diyarbakır with other sesquiterpenelactone-free chamomiles might provide less antiinflammatory potency than chamazulene containing chamomile but are not completely dysfunctional in phytotherapy.…”

Section: Resultsmentioning

confidence: 99%

Diyarbakır/Türkiye’nin Altı Farklı Bölgesinden Toplanan Matricaria chamomilla L. Örneklerinin Kamazulen İçeriği ve Hipoglisemik Potansiyeli

ŞAHİN,

TUNÇ,

ŞEKERCİLER SUBAŞI

2023

Comm. J. Biol.

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Chamomile (Matricaria chamomilla L.) is one of the oldest and most widely known medicinal plants belonging to Asteraceae family. An artifact named chamazulene forms from the sesquiterpene structured lactones such as matricin during the hydro-distillation of flowering tops of chamomile. These compounds are associated with the anti-inflammatory potential of chamomile along with flavonoids, other sesquiterpenoids, and essential oil of the plant. However, not all M. chamomilla specimens grown in different regions or species known and used as chamomile contains sesquiterpene lactone components. Thus, chamazulene content of chamomile has become a pharmaceutical interest. A traditional and well-established indication of the plant is diabetes. Protective and beneficial effects of chamomile on diabetic complications and glycemic control have been proposed by several studies. However, the mechanism of action is yet to be elucidated. Flowering tops of chamomile samples were collected from six different localities of Diyarbakır/Türkiye. Essential oils (EOs) were obtained by hydro-distillation. Petroleum ether (PE), ethyl acetate (EA), methanol (Me), and infusion (INF) extracts were prepared. Qualitative analysis of the EOs resulted in no chamazulene content. Bismil district might be eligible for medicinal chamomile culture with its high essential oil yield. In-vitro hypoglycemic potentials of the extracts and EOs were evaluated by α-glucosidase inhibitory assay. All EOs and EA extracts (except M4-Bismil samples) showed the highest inhibitory activities comparable to that of standard acarbose. α-Glucosidase inhibition might be a significant mechanism of action contributing to the antidiabetic effects of chamomile.

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Section: Resultsmentioning

confidence: 99%

Diyarbakır/Türkiye’nin Altı Farklı Bölgesinden Toplanan Matricaria chamomilla L. Örneklerinin Kamazulen İçeriği ve Hipoglisemik Potansiyeli

ŞAHİN,

TUNÇ,

ŞEKERCİLER SUBAŞI

2023

Comm. J. Biol.

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“…In addition, herbal medicine in the treatment of NE has also been reported. Through randomized, doubleblind, placebo-controlled trials, "chamomile oil" (63), "Urox R " (a capsule of extractive Crataeva nurvala bark, Equisetum arvense stem and Lindera aggregate Sims) (64) and "Suo Quan" (a mixture of Alpinia oxyphylla Miq., Dioscorea opposita Thunb., and Radix Lindera) (65), all of them significantly reduced the frequency of NE and had a low recurrence rate without causing any adverse events (63)(64)(65)(66). Yokukansan (a preparation of kampo) may also be effective, but clinical trials need to be further expanded (67).…”

Section: Treatmentmentioning

confidence: 99%

Bibliometric and visual analysis of nocturnal enuresis from 1982 to 2022

Yang

Tian

et al. 2022

Front. Pediatr.

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Nocturnal enuresis is a common disorder among children that seriously affects physical and mental health and has become a social problem. Bibliometric analysis is a valid way to examine existing research results, current research hotspots and research frontiers. Current studies on nocturnal enuresis are numerous and complex, but a bibliometric analysis of the existing research on nocturnal enuresis has yet to be published. To better identify the research trends and frontiers in nocturnal enuresis, it is necessary to conduct a comprehensive review and analysis. We used bibliometric and visualization methods to analyze the 1,111 papers published between 1982 and 2022 from the Web of Science core collection. Basic information about the country, institution, and authors was analyzed, which led to a basic understanding of nocturnal enuresis. The United States is the most prolific country, Ghent University is the most influential institution, and Rittig Soren is the most prominent scholar. The frequency of keywords, clustering, and the cited literature were analyzed to understand the hotspots and frontiers of research, and a brief review of the highly cited literature was conducted. The current research hotspots are the treatment modalities for nocturnal enuresis, epidemiological investigations, and the exploration of pathogenesis. Clinical research, adenoidectomy, aquaporin 2, and response inhibition are potential research hotspots. The standardization of terminology in nocturnal enuresis and the pathologies of polyuria and sleep disorder are at the forefront of research. In summary, the results of our bibliometric analysis reveal views on the current situation and the trend of nocturnal enuresis research for the first time. This study may provide guidance for promoting research on nocturnal enuresis.

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“…Matricaria chamomilla has been widely employed in several traditional medical traditions. Numerous preclinical and clinical studies have been conducted to evaluate the various activities exhibited by M. chamomilla, including antibacterial, antioxidant, anti-inflammatory, antiulcer, hypoglycemic, hypolipidemic, cardioprotective, hepatoprotective, neuroprotective, nephroprotective, antispasmodic, wound healing, and anticancer properties, as well as medical conditions including anxiety, sleep deprivation, and depression 13 .…”

Section: Introductionmentioning

confidence: 99%

Chamomile (Matricaria chamomilla L.) Essential Oil and its Potential Against Stress, Anxiety, and Sleep Quality

Alvarado Garcia,

Soto-Vasquez,

Rodrigo Villanueva

et al. 2024

Pharmacogn J.

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Matricaria chamomilla: A valuable insight into recent advances in medicinal uses and pharmacological activities

Cited by 22 publications

References 161 publications

Diyarbakır/Türkiye’nin Altı Farklı Bölgesinden Toplanan Matricaria chamomilla L. Örneklerinin Kamazulen İçeriği ve Hipoglisemik Potansiyeli

Diyarbakır/Türkiye’nin Altı Farklı Bölgesinden Toplanan Matricaria chamomilla L. Örneklerinin Kamazulen İçeriği ve Hipoglisemik Potansiyeli

Bibliometric and visual analysis of nocturnal enuresis from 1982 to 2022

Chamomile (Matricaria chamomilla L.) Essential Oil and its Potential Against Stress, Anxiety, and Sleep Quality

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