Mating increases starvation resistance and decreases oxidative stress resistance in <i>Drosophila melanogaster</i> females

Rush, B. L.; Sandver, Sarah; Bruer, Jessica; Roche, R.; Wells, Michael A.; Giebułtowicz, Jadwiga M.

doi:10.1111/j.1474-9726.2007.00322.x

Cited by 40 publications

(33 citation statements)

References 27 publications

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“…On the other hand, our sample of mated males likely included individuals that mated with 0, 1 or more females due to differential mating success before the SR assay and this might have some influence in the reaction norms of males. Similar effects of mating on SR in females have been reported in highly inbred lines with a long history of laboratory rearing (Canton-S and Oregon-R) (Rush et al 2007) and lines selected for increased lifespan (Service 1989). Interestingly, such positive effect of mating on SR does not seem to be restricted to Drosophila.…”

Section: Discussionsupporting

confidence: 58%

The effect of mating on starvation resistance in natural populations of Drosophila melanogaster

et al. 2011

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In nature, behavioural and physiological processes involved in mating may entail different costs and benefits for males and females. However, it has been hypothesized that sexual interactions may have additional costs for Drosophila females like decrease in receptivity to remating and shortening of lifespan. During mating, males transfer seminal fluid proteins to females that exert severe physiological changes that may compromise female's lifespan and reproductive success. However, under specific stressful environmental conditions that organisms usually face in nature, mating may also confer benefits to females. In the present work, we examine the effect of mating on starvation resistance in wild Drosophila melanogaster. We demonstrate that mated females derived from different geographic locations have the benefit of a greater starvation resistance as compared to virgin females. Even though mating status did not affect mean starvation resistance, we detected a strong genotype-specific effect in males. Beyond the obvious advantage of mating, our study reveals that mating might not be perilous for females, as envisaged by sexual conflict theories, but advantageous for flies exposed to shifts in environmental conditions. Thus, our results highlight the importance of studying other ecologically relevant traits that may contribute to the evolution of male-female interactions.

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Section: Discussionsupporting

confidence: 58%

The effect of mating on starvation resistance in natural populations of Drosophila melanogaster

et al. 2011

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“…One study found that D. melanogaster females that were mated and had high levels of reproduction were significantly more resistant to starvation compared with age-matched virgin females. However, these mated females had a significantly lower resistance to oxidative stress compared with virgin females (58), indicating that reproduction influences stress responses. In C. elegans, stressed (heat shock, osmotic shock, and anoxia) or quiescent oocytes have altered germ line morphology.…”

mentioning

confidence: 97%

“…There is evidence that reproduction influences various biological processes including stress responses and longevity (19,48,58,72). One study found that D. melanogaster females that were mated and had high levels of reproduction were significantly more resistant to starvation compared with age-matched virgin females.…”

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confidence: 99%

Reduction in ovulation or male sex phenotype increases long-term anoxia survival in adaf-16-independent manner inCaenorhabditis elegans

Mendenhall

LeBlanc

Mohan

et al. 2009

Physiological Genomics

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Mendenhall AR, LeBlanc MG, Mohan DP, Padilla PA. Reduction in ovulation or male sex phenotype increases long-term anoxia survival in a daf-16-independent manner in Caenorhabditis elegans. Physiol Genomics 36: 167-178, 2009. First published December 2, 2008 doi:10.1152/physiolgenomics.90278.2008.-Identifying genotypes and phenotypes that enhance an organism's ability to survive stress is of interest. We used Caenorhabditis elegans mutants, RNA interference (RNAi), and the chemical 5-fluorodeoxyuridine (FUDR) to test the hypothesis that a reduction in progeny would increase oxygen deprivation (anoxia) survival. In the hermaphrodite gonad, germ line processes such as spermatogenesis and oogenesis can be simultaneously as well as independently disrupted by genetic mutations. We analyzed genetic mutants [glp-1(q158), glp-4(bn2ts), plc-1(rx1), ksr-1(ku68), fog-2(q71), fem-3(q20), spe-9(hc52ts), fer-15(hc15ts)] with reduced progeny production due to various reproductive defects. Furthermore, we used RNAi to inhibit the function of gene products in the RTK/Ras/MAPK signaling pathway, which is known to be involved in a variety of developmental processes including gonad function. We determined that reduced progeny production or complete sterility enhanced anoxia survival except in the case of sterile hermaphrodites [spe-9(hc52ts), fer-15(hc15ts)] undergoing oocyte maturation and ovulation as exhibited by the presence of laid unfertilized oocytes. Furthermore, the fog-2(q71) long-term anoxia survival phenotype was suppressed when oocyte maturation and ovulation were induced by mating with males that have functional or nonfunctional sperm. The mutants with a reduced progeny production survive long-term anoxia in a daf-16-and hif-1-independent manner. Finally, we determined that wild-type males were able to survive long-term anoxia in a daf-16-independent manner. Together, these results suggest that the insulin signaling pathway is not the only mechanism to survive oxygen deprivation and that altering gonad function, in particular oocyte maturation and ovulation, leads to a physiological state conducive for oxygen deprivation survival. oxygen deprivation; germ line; insulin-like signaling; stress; anoxia METAZOANS INHABITING aquatic or subterranean ecosystems have evolved mechanisms to survive changes in oxygen levels. For example, repression of energy-requiring processes or reallocation of metabolism increases oxygen deprivation survival (21). Although most terrestrial organisms live in environments where the oxygen tension does not fluctuate much, they do have the capacity to sense and respond to oxygen deprivation. In humans, oxygen deprivation is central to various health conditions including myocardial infarction, stroke, blood loss, pulmonary disorders, and solid tumor progression (37, 62). Thus identifying the molecular mechanisms that govern metazoan response to and survival of oxygen deprivation is of great interest.Oxygen deprivation tolerance spans across various phyla (7,20,53,55,68). The comparison of oxygen d...

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“…In Drosophila, individuals resist starvation as a function of the extent of their fat stores, and fat stores, in turn, vary with reproductive status and age (e.g. Chippindale et al, 1996;Rush et al, 2007;Goenaga et al, 2012Goenaga et al, , 2013Lee et al, 2013;Lee and Jang, 2014;Lee, 2015).…”

Section: Introductionmentioning

confidence: 99%

Resistance to nutritional stress in ants: when being fat is advantageous

Dussutour

Poissonnier

Buhl

et al. 2016

Journal of Experimental Biology

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In ants, nutrient acquisition for the whole colony relies on a minority of workers, the foragers, which are often old and lean. Some studies have shown that the link between age, physiology and foraging activity is more flexible than once thought, especially in response to colony or environmental perturbations. This great plasticity offers the intriguing possibility to disentangle the effect of age, behaviour and physiology on the ants' abilities to cope with nutritional stresses. In this paper, we first looked at the capacity of groups of foragers and inner-nest workers to resist starvation and macronutrient imbalance. Second, we investigated whether behavioural task reversion modified the tolerance to nutritional stresses and by extension, changed mortality rate. We found that inner-nest workers live longer than foragers under nutritional stresses but not under optimal conditions. The reversion from foraging to inner-nest activities is followed by an increase in fat content and longevity. Finally, we demonstrated that changes in fat content associated with behavioural transition are highly flexible and strongly correlated to tolerance of nutritional stress. Our results have considerable implications for our understanding of the population dynamics of social insects under adverse nutritional conditions.

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Mating increases starvation resistance and decreases oxidative stress resistance in Drosophila melanogaster females

Cited by 40 publications

References 27 publications

The effect of mating on starvation resistance in natural populations of Drosophila melanogaster

The effect of mating on starvation resistance in natural populations of Drosophila melanogaster

Reduction in ovulation or male sex phenotype increases long-term anoxia survival in adaf-16-independent manner inCaenorhabditis elegans

Resistance to nutritional stress in ants: when being fat is advantageous

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