Mathematical models of drug-resistant tuberculosis lack bacterial heterogeneity: A systematic review
Naomi M. Fuller,
Christopher F. McQuaid,
Martin J. Harker
et al.
Abstract:Drug-resistant tuberculosis (DR-TB) threatens progress in the control of TB. Mathematical models are increasingly being used to guide public health decisions on managing both antimicrobial resistance (AMR) and TB. It is important to consider bacterial heterogeneity in models as it can have consequences for predictions of resistance prevalence, which may affect decision-making. We conducted a systematic review of published mathematical models to determine the modelling landscape and to explore methods for inclu… Show more
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