2012
DOI: 10.1111/j.1525-1594.2012.01464.x
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Mathematical Modeling of Thermal and Circulatory Effects During Hemodialysis

Abstract: Intradialytic hypotension (IDH) is one of the most common complications of hemodialysis (HD) treatment. The initiating factor of IDH is a decrease in blood volume, which is related to an imbalance between ultrafiltration (UF) and refilling rate. Impaired reactivity of resistance and capacitance vessels in reaction to hypovolemia plays possibly a major role in the occurrence of IDH. These vessels also fulfill an important function in body temperature regulation. UF-induced cutaneous vasoconstriction would resul… Show more

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Cited by 10 publications
(4 citation statements)
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“…Droog et al. of Eindhoven University of Technology, Eindhoven, The Netherlands developed a mathematical model that can provide insight into the impact of thermoregulatory processes on the cardiovascular system during hemodialysis (HD) treatment. Model simulations for isothermal versus thermoneutral HD+ultrafiltration (UF) were compared with measurement data of patients on chronic intermittent HD.…”
Section: Renal Support and Dialysismentioning
confidence: 99%
“…Droog et al. of Eindhoven University of Technology, Eindhoven, The Netherlands developed a mathematical model that can provide insight into the impact of thermoregulatory processes on the cardiovascular system during hemodialysis (HD) treatment. Model simulations for isothermal versus thermoneutral HD+ultrafiltration (UF) were compared with measurement data of patients on chronic intermittent HD.…”
Section: Renal Support and Dialysismentioning
confidence: 99%
“…Indeed, cold dialysis (CD), has been proposed that attenuates the risk for patient hyperthermia compared to typical dialysis (dialysate temperature at 37°C; TD) and leads to cutaneous vasoconstriction [12]. These observations have led to a growing interest in the thermal and circulatory adaptations occurring during CD [13]. Yet, the precise changes in body heat balance during either CD or TD remain poorly documented and understood.…”
Section: Introductionmentioning
confidence: 99%
“…Indeed, cold dialysis (CD) attenuates the risk for patient hyperthermia compared to typical dialysis (dialysate temperature at 37 °C; TD) and leads to cutaneous vasoconstriction (12). These observations have led to a growing interest in the thermal and circulatory adaptations occurring during CD (13). Yet, the precise changes in body heat balance during either CD or TD remain poorly documented and understood.…”
Section: Introductionmentioning
confidence: 99%