2014
DOI: 10.5897/ajmr2013.6455
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Mathematical modeling of some medium constituents and its impact on the production of vitamin B12 and folic acid by Klebsiella pneumoniae under solid state fermentation

Abstract: The present investigation involved testing the effect of different carbon sources (glucose, sucrose and starch) as well as different nitrogen sources (peptone, yeast extract and urea) on the production of vitamin B 12 using Klebsiella pneumonia grown on mixture of agriculture wastes (wheat straw and rice bran). The results show that glucose was the best carbon source compared to the other di-and polysaccharides used. The best vitamin B 12 output (63.87 µg/L) was obtained at 3 g/L glucose. On the other hand, pe… Show more

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