Mathematical modeling in autoimmune diseases: from theory to clinical application
Yaroslav Ugolkov,
Antonina Nikitich,
Cristina Leon
et al.
Abstract:The research & development (R&D) of novel therapeutic agents for the treatment of autoimmune diseases is challenged by highly complex pathogenesis and multiple etiologies of these conditions. The number of targeted therapies available on the market is limited, whereas the prevalence of autoimmune conditions in the global population continues to rise. Mathematical modeling of biological systems is an essential tool which may be applied in support of decision-making across R&D drug progra… Show more
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