In the present study, fractional variants of Hermite–Hadamard, Hermite–Hadamard–Fejér, and Pachpatte inequalities are studied by employing Mercer concept. Firstly, new Hermite–Hadamard–Mercer-type inequalities are presented for harmonically convex functions involving fractional integral operators with exponential kernel. Then, weighted Hadamard–Fejér–Mercer-type inequalities involving exponential function as kernel are proved. Finally, Pachpatte–Mercer-type inequalities for products of harmonically convex functions via fractional integral operators with exponential kernel are constructed.