Maternal transfer of dechloranes and their distribution among tissues in contaminated ducks

Abstract

h i g h l i g h t sRelatively serious contamination of DP was found in the e-waste recycling sites, Taizhou. Lipid pool, liver sequestration and blood-barrier affect tissue distribution of DP and its analogues. The maternal transfer extent of Dec 602 was over one. The stereo-selective accumulation of DP occurs among duck tissues. The monodechlorinated products in duck likely originated from the exterior environment. a r t i c l e i n f o t r a c tThe tissue concentrations of dechlorane plus and its analogues were determined in ducks collected from several e-waste recycling villages of Taizhou, China. Compared with the published literature, the relatively high concentrations of these compounds were detected in ducks, indicating serious DP contamination. Since both the duck meat and eggs were important components for diet, this result reminded us of keeping a watchful eye on human dietary exposure to DP and its analogues in this study area. The wetweight concentrations of DP and its analogues were significantly related to tissue lipid content (p < 0.05), indicating that the lipid pools predominantly impacted the distribution of DPs in ducks. On the basis of lipid adjustment, the significantly lower levels in brain than those in liver and blood, displayed the occurrence of liver sequestration and bloodebrain barrier to DP and its analogues in the duck (p < 0.05). The maternal transfer of DP and Mirex was not obviously limited, and the transferring extent of Dec 602 was over one. The stereo-selected accumulation of two DP isomers occurred among tissues with preference to syn-DP in blood, and to anti-DP in brain. The values of lipid-adjusted monodechlorinated products mainly originated from the exterior environment in ducks.

E-Waste and Its Consequence for Environment and Public Health: Perspectives in Covid-19 Pandemic Times

“…Number of articles about e-waste recycle between year's 2010 and 2020. These data were obtained from Brazilian Government Data Bank for scientific publications, between year's 2010 to 2020 (Capes, 2000) The articles about contamination really represents the presence of e-waste chemical pollutants in the water (Wu et al, 2015), soil (Quan et al, 2015), plants (Wang et al, 2012), animals (Wu et al, 2016), and humans (Asante et al, 2012) near recycling areas (Figure 5). The articles about recycling (Figure 6) represents not only formal recycle, but mainly unconventional and dangerous recycle methods for environment.…”

Comparison of Dechlorane Plus Concentrations in Sequential Blood Samples of Pregnant Women in Taizhou, China

“…DP exhibits some POP-like properties, one of which is its ability to accumulate in animals and humans [ 2 , 4 , 5 ]. Studies on animals [ 6 , 7 ] (e.g., fish and poultry) have given evidence on DP transfer from parents to offspring, and Ben’s study [ 8 ] further confirmed the transplacental transfer of DP in humans. Although its health risk to humans has not yet been better understood until now, animal experiments have shown that exposure to DP in early life could impact axonal growth, musculature, and motor behavior in embryo–larval zebrafish [ 9 ], and regulate mRNA expression in chicken embryos [ 10 ].…”

“…Due to the significant linkage between prenatal exposure and adverse health outcomes at birth and/or in later life, exposure of pregnant women to persistent organic contaminants is an ongoing public health concern [ 11 ]. The transplacental transfer and potential toxicity to animals [ 6 , 7 ], together with POP-like properties [ 2 , 4 , 5 ], implies that we ought to pay specific concern to in utero exposure to DP in humans.…”

Toxic effects of dechlorane plus on the common carp (Cyprinus carpio) embryonic development

“…Dechlorane Plus (DP) is a polychlorinated flame retardant designed to replace Brominated flame retardants or Mirex (Ji et al, 2018 ), and it is widely used in plastic roofing materials, electrical wires, hard disk connectors of computers, and other polymeric systems (Ren et al 2008). DP is found common in the aquatic environment Sun et al 2017;Tao et al 2015;Wu et al 2016), with a half-life of about 24 years in the water environment. It is a typical persistent organic pollutant and has an effect of bio-enrichment and bio-fortification in the biota (OxyChem 2007;Yu et al 2013).…”

“…Hoh et al first discovered the existence of DP in the environment in 2006. Some studies show that DP accumulates in female herring gulls, crucian carp, ducks, lake trout, and mud carps, and that it is maternally transferred to their eggs (Guo et al 2017;Gauthier and Letcher 2009;Wu et al 2016).…”