Maternal serological screening for cytomegalovirus infection may play an important role nowadays

Abstract

Dear editor,We read with great interest the recent publication by Dr. Xie and colleagues entitled "Serological screening for cytomegalovirus during pregnancy: A systematic review of clinical practice guidelines and consensus statements."In their comprehensive systematic review, the authors found that none of the clinical practice guidelines or consensus statements recommended universal serological screening for cytomegalovirus (CMV) in pregnant women. 1 This strategy is often legitimized by valid and complex reasons, such as the inability of laboratory tests to predict which newborn will develop long-term hearing loss or other neurodevelopmental complications, and the potentially increased rate of unnecessary abortions. 2,3 However, we fully agree with the authors that the current recommendations are characterized by limited and low-level evidence, 1 and we would like to emphasize some important concepts.