Abstract:Rationale: Maternal psychosocial stress might be associated with development of allergic diseases in the offspring.Objectives: To evaluate the association of maternal depression and anxiety with ever wheezing and recurrent wheezing among infants and to assess the role of maternal hypothalamo-pituatary-adrenal axis changes and fetal immune response in this association.Methods: This study encompasses two designs; cohort design was developed to evaluate the association of prenatal depression with development of w… Show more
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