“…It contains a number of distinctive domains of which the most conserved is the Ceratitis-Apis-Musca (CAM) domain, which is believed to implement the autoregulatory splicing loop of tra (Hediger et al, 2010). It has been found in all investigated tra orthologues, including those of Tribolium castaneum, Apis mellifera, Nasonia vitripennis, Asobara tabida and various dipterans, with the exception of drosophilids (Pane et al, 2005;Lagos et al, 2007;Ruiz et al, 2007;Hasselmann et al, 2008a;Hediger et al, 2010;Verhulst et al, 2010b;Saccone et al, 2011;Shukla and Palli, 2012;Geuverink et al, 2018). TRA also possesses order-specific domains, one of which is only shared amongst the Diptera (the DIP domain) and another that is only present in the Hymenoptera (the HYM domain) (Verhulst et al, 2010b).…”