Maternal mortality: The role of Mycoplasma hominis and its impact on neonatal health

Poku, Vivian Osei

doi:10.1016/j.hsr.2022.100036

Cited by 3 publications

(1 citation statement)

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“…Mycoplasma hominis ( M. hominis ) commonly colonizes the genitourinary tract in a nonvirulent manner ( Whitson et al., 2014 ). Nevertheless, it is an opportunistic pathogen that can cause a variety of genitourinary or extragenital infections, as well as neonatal infections ( Poku, 2022 ; Zeng et al., 2022 ). However, this pathogen is commonly underestimated and overlooked in clinical settings due to undetermined pathogenic processes ( Ahmed et al., 2021 ).…”

Section: Introductionmentioning

confidence: 99%

Case Report: Double trouble: a rare case of successfully treated Mycoplasma hominis and Pseudomonas aeruginosa co-infection

Shi-mei

Tang

Wang

et al. 2023

Front. Cell. Infect. Microbiol.

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BackgroundExtra-urogenital infections due to Mycoplasma hominis (M. hominis) are rare, particularly co-infection with Pseudomonas aeruginosa (P. aeruginosa). Herein, we report on a patient who was co-infected and successfully treated despite delayed treatment.Case presentationWe reported the case of a 43-year-old man with M. hominis and P. aeruginosa co-infection after a traffic accident. The patient developed a fever and severe infection despite postoperative antimicrobial therapies. The blood culture of wound tissues was positive for P. aeruginosa. Meanwhile, culturing of blood and wound samples showed pinpoint-sized colonies on blood agar plates and fried-egg-type colonies on mycoplasma medium, which were identified as M. hominis by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) and 16S rRNA sequencing. Based on antibiotic susceptibility and symptoms, ceftazidime–avibactam and moxifloxacin were administered for P. aeruginosa infection. Meanwhile, after the failure of a series of anti-infective agents, M. hominis and P. aeruginosa co-infection was successfully treated with a minocycline-based regimen and polymyxin B.ConclusionThe co-infection with M. hominis and P. aeruginosa was successfully treated with anti-infective agents despite delayed treatment, providing information for the management of double infection.

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