Maternal Mortality:

Anderson, Frank W.

doi:10.1097/grf.0b013e3181a4bd53

Cited by 16 publications

(5 citation statements)

References 21 publications

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“…In the United States, the probability is 1 : 3,700 [5]. Direct obstetric causes of these conditions are consistent with those recorded in other parts of the world: bleeding (antepartum and postpartum), preeclampsia, sepsis, prolonged labor, obstructed labor, and complications related to abortion [1, 6]. …”

Section: Introductionsupporting

confidence: 56%

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Severe Postpartum Hemorrhage from Uterine Atony: A Multicentric Study

Montúfar-Rueda

Rodriguez²,

Jarquin³

et al. 2013

Journal of Pregnancy

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Objective. Postpartum hemorrhage (PPH) is an important cause of maternal mortality (MM) around the world. Seventy percent of the PPH corresponds to uterine atony. The objective of our study was to evaluate multicenter PPH cases during a 10-month period, and evaluate severe postpartum hemorrhage management. Study Design. The study population is a cohort of vaginal delivery and cesarean section patients with severe postpartum hemorrhage secondary to uterine atony. The study was designed as a descriptive, prospective, longitudinal, and multicenter study, during 10 months in 13 teaching hospitals. Results. Total live births during the study period were 124,019 with 218 patients (0.17%) with severe postpartum hemorrhage (SPHH). Total maternal deaths were 8, for mortality rate of 3.6% and a MM rate of 6.45/100,000 live births (LB). Maternal deaths were associated with inadequate transfusion therapy. Conclusions. In all patients with severe hemorrhage and subsequent hypovolemic shock, the most important therapy is intravascular volume resuscitation, to reduce the possibility of target organ damage and death. Similarly, the current proposals of transfusion therapy in severe or massive hemorrhage point to early transfusion of blood products and use of fresh frozen plasma, in addition to packed red blood cells, to prevent maternal deaths.

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Section: Introductionsupporting

confidence: 56%

“…Postpartum hemorrhage (PPH) is a major cause of MM around the world with incidence of 2–11% [1–3]. According to the World Health Organization, 10.5% of live births were complicated with PPH, and reports from 2000 show that 13,795,000 women suffered PPH accounting for 13,200 of maternal deaths [4].…”

Section: Introductionmentioning

confidence: 99%

Severe Postpartum Hemorrhage from Uterine Atony: A Multicentric Study

Montúfar-Rueda

Rodriguez²,

Jarquin³

et al. 2013

Journal of Pregnancy

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“…Globally the incidence of postpartum hemorrhage (PPH) ranges from 2% -11%, with variation among countries [31]. In this study, the incidence of PPH has been fluctuating over the years with a minimum of 1.78% and a maximum of 2.87.…”

Section: Discussionmentioning

confidence: 87%

Postpartum Hemorrhage: Incidence, Causes and Maternal Outcomes at Muhimbili National Hospital, Tanzania—A Retrospective Descriptive Hospital-Based Study

Mjema,

Kikula,

August

et al. 2023

OJOG

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Worldwide obstetric hemorrhage remains the leading cause of maternal mortality, accounting for over one quarter of maternal deaths. Over half of these deaths occur in Sub-Saharan Africa with mortality rates of 500 -1000 per 100,000 births, compared to approximately 5 -10 in developed countries. Over decades in Sub Saharan Africa preventive measures and treatment protocols have been made to reduce maternal mortality caused by PPH. While rates of postpartum hemorrhage have continued to rise, there is a need to evaluate if its etiology and patterns have changed over time. Broad Objective: This study aims at describing trends in incidence, causes and maternal outcomes of Postpartum Hemorrhage at Muhimbili National Hospital for a period of 7 years. Methodology: This is a retrospective descriptive hospital-based study that has included all cases of postpartum hemorrhage at Muhimbili National Hospital, a tertiary hospital in Tanzania from 2014 to 2020. The data was analyzed using SPSS Version 26 and presented using frequency tables, figures and percentages. The trends of postpartum hemorrhage over time were determined using chi-square test and P-value where less than 0.05 was considered statistically significant. Results: Overall, the incidence of postpartum hemorrhage has been fluctuating over the years with minimum

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“…The spontaneous abortion rate increases to 15% for ages 30-34, is approximately 25% for ages 35-39, 51% for ages 40-44, and peaks after age 45 over to >93%. 8 It is now known that donor egg IVF in women with poor ovarian reserve testing has been shown associated with: 1) Increased pregnancy rates compared with autologous eggs; and.…”

Section: Role Of Lmwh In Apsmentioning

confidence: 99%

Immunological Causes of Bad Obstetric History

Koppad¹,

Lakshmi²

2014

jebmh

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Occurrence of three consecutive pregnancy losses constitutes the classic definition of bad obstetric history (BOH). One of the important causes of BOH is the presence of antiphospholipid antibodies, which enhance the coagulability of blood in pregnancy. The association between phospholipid antibodies and recurrent miscarriage is called Antiphospholipid Syndrome (APS). Pregnant women with thrombotic APS have higher rates of pregnancy complications. APS is responsible for first trimester pregnancy loss in 90% of patients. APS is associated with events like thrombosis, vascular injury and vasoconstriction, all of which can abnormally reduce maternal-fetal interface blood flow. APS is best treated by a combination of LMWH and low-dose aspirin. Controlled clinical studies have demonstrated the superiority of heparin plus aspirin over aspirin alone in improving the birth rate.

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Maternal Mortality:

Cited by 16 publications

References 21 publications

Severe Postpartum Hemorrhage from Uterine Atony: A Multicentric Study

Severe Postpartum Hemorrhage from Uterine Atony: A Multicentric Study

Postpartum Hemorrhage: Incidence, Causes and Maternal Outcomes at Muhimbili National Hospital, Tanzania—A Retrospective Descriptive Hospital-Based Study

Immunological Causes of Bad Obstetric History

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