Maternal methylosome protein 50 is essential for embryonic development in medaka Oryzias latipes
Shi Duan,
Qing Yang,
Fan Wu
et al.
Abstract:Methylosome protein 50 (Mep50) is a protein that is rich in WD40 domains, which mediate and regulate a variety of physiological processes in organisms. Previous studies indicated the necessity of Mep50 in embryogenesis in mice Mus musculus and fish. This study aimed to further understand the roles of maternal Mep50 in early embryogenesis using medaka Oryzias latipes as a model. Without maternal Mep50, medaka zygotes developed to the pre‐early gastrula stage but died later. The transcriptome of the embryos at t… Show more
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