Maternal inheritance of extranuclear mitochondrial markers in<i>Aspergillus nidulans</i>

Rowlands, Robert T.; Turner, Geoffrey

doi:10.1017/s0016672300016979

Cited by 17 publications

(12 citation statements)

References 22 publications

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“…During this sequence, the extranuclear genomes, including mtDNAs, generally do not recombine, because of their strict uniparental inheritance (Birky 1978(Birky , 1983(Birky , 1994. Most fungi and other eukaryotic microbes are characterised by predominantly maternal inheritance of their cytoplasmic DNAs, as has been reported in many cases (Rowlands and Turner 1976;Brasier and Kirk 1986;Martin 1989;Specht et al 1992;Wilch et al 1992;Lee and Taylor 1993;Whittaker et al 1994;Chung et al 1996;Coenen et al 1996). There are only a few exceptions known where paternal inheritance of extranuclear genomes also occurs.…”

Section: Introductionmentioning

confidence: 91%

Recombination of mitochondrial DNAs following transmission of mitochondria among incompatible strains of black Aspergilli

Kevei¹,

Töth²,

Coenen

et al. 1997

Mol Gen Genet

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Successful intra- and interspecific mitochondrial transfers were performed by polyethylene glycol (PEG)-induced protoplast fusion among incompatible strains belonging to the Aspergillus niger species aggregate. The mitochondrial DNAs (mtDNAs) of the strains examined were of three main types based on their restriction fragment length polymorphism (RFLP) profiles. mtDNA types 1 and 2 correspond to A. niger and A. tubingensis species, respectively, while type 3 is represented by some Brazilian wild-type isolates (possibly a distinct species or subspecies). mtDNA types 1 and 2 could be further divided into several subgroups (1a-1e and 2a-2f). All these strains, representing different RFLP groups or subgroups, were fully incompatible with respect to nuclear complementation. The transfer experiments were carried out under selection pressure, using a mitochondrial oligomycin-resistant mutant of mtDNA type 1a as donor. Following fusion mitochondrial oligomycin-resistant progenies were recovered in the presence of oligomycin by selecting for the nuclear phenotypes of the oligomycin-sensitive recipient strains. All attempted transfers were successful, and resulted in different varieties of resistant recombinant mitochondrial progenies at various frequencies. Within the group of strains of mtDNA type 1, the transfer of oligomycin-resistant mitochondria resulted in the appearance of a single recombinant type of RFLP profile in each case. The recombination events were more complex when the transfer of oligomycin resistance occurred between strains representing different species (mtDNA groups 1a-->2 and 1a-->3). A great variety of recombinant mtDNA RFLP profiles appeared. Explanation for this phenomenon are discussed on the basis of preliminary physical mapping data.

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Section: Introductionmentioning

confidence: 91%

Recombination of mitochondrial DNAs following transmission of mitochondria among incompatible strains of black Aspergilli

Kevei¹,

Töth²,

Coenen

et al. 1997

Mol Gen Genet

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“…This avenue of sexual reproduction might be viewed as the only exception to the rule that all organisms produce some uniparental zygotes. But the mitochondrial genes are inherited maternally, through the cleistothecial parent, in sexual crosses between heterokaryon-incompatible strains in which nuclei migrate only a short distance from each mycelium into the other (35).…”

Section: Geneticsmentioning

confidence: 99%

Uniparental inheritance of mitochondrial and chloroplast genes: mechanisms and evolution.

Birky

1995

Proc. Natl. Acad. Sci. U.S.A.

798

565

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In nearly all eukaryotes, at least some individuals inherit mitochondrial and chloroplast genes from only one parent. There is no single mechanism of uniparental inheritance: organelle gene inheritance is blocked by a variety of mechanisms and at different stages of reproduction in different species. Frequent changes in the pattern of organelle gene inheritance during evolution suggest that it is subject to varying selective pressures. Organelle genes often fail to recombine even when inherited biparentally; consequently, their inheritance is asexual. Sexual reproduction is apparently less important for genes in organelles than for nuclear genes, probably because there are fewer of them. As a result organelle sex can be lost because of selection for special reproductive features such as oogamy or because uniparental inheritance reduces the spread of cytoplasmic parasites and selfish organelle DNA.

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“…An extensive search for biparental inheritance in crosses of different (heterokaryon incompatible) wild-types has never been performed. Rowlands & Turner (1976) performed crosses between two heterokaryon incompatible strains, he-Glasgow and hc-B (Croft, 1985). In four separate crosses between these strains they examined a total of 79 hybrid cleistothecia.…”

Section: Introductionmentioning

confidence: 99%

“…Zonneveld (1988) observed hyphae differing from vegetative hyphae and suggested that these were dikaryotic. Rowlands & Turner (1976) used mutations of the mitochondrial genome to determine from which parent the ascospores in a cleistothecium inherited their mitochondria. This parent they called the maternal parent.…”

Section: Introductionmentioning

confidence: 99%

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Mitochondrial inheritance inAspergillus nidulans

et al. 1996

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Mitochondrial chloramphenicol and oligomycin resistance mutations were used to investigate mitochondrial inheritance in A. nidulans. Mitochondrial RFLPs could not be used to distinguish between paternal and maternal mitochondria because none were detected in the 54 isolates investigated. Several thousand ascospores from each of 111 hybrid cleistothecia from 21 different crosses between 7 heterokaryon incompatible isolates were tested for biparental inheritance. All mitochondrial inheritance was strictly uniparental. Not one instance of paternal inheritance of mitochondria was observed. The implications of our results for the theory that uniparental inheritance evolved to avoid cytoplasmic conflict are discussed. Possible explanations for the maintenance of strict uniparental inheritance of mitochondria in an inbreeding homothallic organism are suggested. The chloramphenicol resistance marker was inherited preferentially to the oligomycin resistance marker probably due to the inhibited energy production of mitochondria with the oligomycin resistance mutation. The maternal parent was determined for 93 hybrid cleistothecia from 17 crosses between 7 different strains. Contrary to previous reports A. nidulans strains functioned as both maternal and paternal parent in most crosses.

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Maternal inheritance of extranuclear mitochondrial markers inAspergillus nidulans

Cited by 17 publications

References 22 publications

Recombination of mitochondrial DNAs following transmission of mitochondria among incompatible strains of black Aspergilli

Recombination of mitochondrial DNAs following transmission of mitochondria among incompatible strains of black Aspergilli

Uniparental inheritance of mitochondrial and chloroplast genes: mechanisms and evolution.

Mitochondrial inheritance inAspergillus nidulans

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