2020
DOI: 10.1016/b978-0-444-64150-2.00029-0
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Maternal infections

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Cited by 8 publications
(5 citation statements)
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“…Congenital infections were defined as infections transmitted from mother to baby transplacentally (during pregnancy) or peripartum (during delivery). 9 Early onset sepsis refers to clinical manifestation of infection within the first 72 hours of life with late onset sepsis occurring after 72 hours of life. 10 Proven sepsis was defined as the presence of laboratory and clinical findings with a positive culture taken from a normally sterile site.…”
Section: Methodsmentioning
confidence: 99%
“…Congenital infections were defined as infections transmitted from mother to baby transplacentally (during pregnancy) or peripartum (during delivery). 9 Early onset sepsis refers to clinical manifestation of infection within the first 72 hours of life with late onset sepsis occurring after 72 hours of life. 10 Proven sepsis was defined as the presence of laboratory and clinical findings with a positive culture taken from a normally sterile site.…”
Section: Methodsmentioning
confidence: 99%
“…Congenital infections of the unborn fetus or newborn infant are a widespread issue caused by pathogens such as the TORCH pathogens and other emerging pathogens such as Zika virus (ZIKV) (Boucoiran et al, 2020;Coyne and Lazear, 2016). These frequently disrupt fetal development, particularly in the brain, resulting in a wide range of symptoms, including damage to sensory organs, birth defects such as microcephaly, or learning and behavioral disorders (Boucoiran et al, 2020;Canetta et al, 2016). Pathogens often target neural stem cells (NSCs) and neural progenitor cells (NPCs), inducing apoptosis, curtailing proliferation, and impairing the differentiation of these cells (Boucoiran et al, 2020;Kamte et al, 2021).…”
Section: Introductionmentioning
confidence: 99%
“…These frequently disrupt fetal development, particularly in the brain, resulting in a wide range of symptoms, including damage to sensory organs, birth defects such as microcephaly, or learning and behavioral disorders (Boucoiran et al, 2020;Canetta et al, 2016). Pathogens often target neural stem cells (NSCs) and neural progenitor cells (NPCs), inducing apoptosis, curtailing proliferation, and impairing the differentiation of these cells (Boucoiran et al, 2020;Kamte et al, 2021). Interestingly, these effects are often caused, not only by the direct influence of infection, but as the indirect result of the immune response, as cytokines and chemokines have been shown to have significant effects on NSC/NPC proliferation, survival, and differentiation (Boucoiran et al, 2020;Chandwani et al, 2019;Kamte et al, 2021).…”
Section: Introductionmentioning
confidence: 99%
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