Maternal immune activation induces sex-dependent behavioral differences in a rat model of schizophrenia
Yunxia Liu,
Xiaoyi Hang,
Yijie Zhang
et al.
Abstract:BackgroundMaternal immune activation (MIA) is a mature means to construct a schizophrenia model. However, some preclinical studies have reported that a MIA-induced schizophrenia model seemed to have gender heterogeneity in behavioral phenotype. On the other hand, the MIA’s paradigms were diverse in different studies, and many details could affect the effect of MIA. To some extent, it is not credible and scientific to directly compare the gender differences of different MIA programs. Therefore, it is necessary … Show more
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