“…We acknowledge that specifying processes for Latinos from different countries of origin is important as there is significant variability across the Latino populations in the United States. For example, among a host of differences, Latinos vary on immigration patterns (Knight, Roosa, & Umaña-Taylor, 2009), composition and structure of the home (Updegraff & Umaña-Taylor, 2015), socio-economic status (Lopez, Gonzalez-Barrera, & Cuddington, 2013), nativity status (Lopez et al, 2013), the protective effects of cultural value endorsement (Calzada, Huang, Linares-Torres, Singh, & Brotman, 2014), experiences of discrimination (P erez, Fortuna, & Alegr ıa, 2008), and epidemiological risk for mental health and substance use problems (Alegr ıa et al, 2007). To best understand how culturally relevant processes are implicated in prevention and intervention research, we argue that many of these factors (i.e., acculturation, cultural value endorsement) need to be empirically examined as potential moderators or mediators of treatment.…”