Maternal Diseases Complicating Pregnancy: Diabetes, Tumors, Preeclampsia, Lupus Anticoagulant

Benirschke, Kurt; Kaufmann, Peter

doi:10.1007/978-3-642-23941-0_19

Cited by 11 publications

(8 citation statements)

References 521 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…All sections were counterstained with hematoxylin and observed under a brightfield microscope. DV was defined as vascular fibrinoid necrosis and lipid-filled foam cells in the vascular wall of spiral arteries in the decidua basalis or parietalis [16,17]. Hence, pregnancies with PE were further divided into two subgroups: without DV (n ¼ 38) and with DV (n ¼ 52).…”

Section: Tissue Sample Collectionmentioning

confidence: 99%

The defect of both angiogenesis and lymphangiogenesis is involved in preeclampsia

Liu

Zhang

et al. 2015

Placenta

View full text Add to dashboard Cite

Section: Tissue Sample Collectionmentioning

confidence: 99%

The defect of both angiogenesis and lymphangiogenesis is involved in preeclampsia

Liu

Zhang

et al. 2015

Placenta

View full text Add to dashboard Cite

“…Placental abruption diagnoses in the absence of disc-impacting blood clots could occur in very acute abruptions in which clots do not have time to organise and cause tissue reactions before delivery. 33 We found that microscopic haemorrhage was modestly associated with PTD < 37 weeks (mutually adjusted OR = 1.6) and PTD < 35 weeks (mutually adjusted OR = 2.4), and these associations remained after maternal demographic characteristics and hypertension were added to the models. Although it is possible that findings in this construct represent intermediate steps on a pathway that sometimes leads to overt placental abruption, most cases of placental abruption (63%, see Table 2) did not have high scores on this construct.…”

Section: Discussionmentioning

confidence: 70%

“…Disc‐impacting blood clots undiagnosed as placental abruption may signal concealed (possibly intraplacental or dissecting) haemorrhage, a less severe clinical picture, or a case with a low index of suspicion for placental abruption. Placental abruption diagnoses in the absence of disc‐impacting blood clots could occur in very acute abruptions in which clots do not have time to organise and cause tissue reactions before delivery 33 …”

Section: Discussionmentioning

confidence: 99%

Evidence of placental haemorrhage and preterm delivery

Gargano

Holzman

Senagore

et al. 2010

BJOG

View full text Add to dashboard Cite

Please cite this paper as: Gargano J, Holzman C, Senagore P, Reuss M, Pathak D, Williams M, Fisher R. Evidence of placental haemorrhage and preterm delivery. BJOG 2010;117:445–455. Objective To evaluate evidence of placental haemorrhage (PH) obtained through maternal interviews, patient charts and placental pathology examinations as potential indicators of a ‘bleeding pathway’ to preterm delivery (PTD). Design Prospective cohort. Setting Fifty‐two clinics in five communities in Michigan, USA (1998–2004). Population A subset (n = 996) of cohort participants with complete placental pathology data. Methods First‐trimester bleeding and placental abruption were ascertained by mid‐trimester interviews and chart review, respectively. Disc‐impacting blood clot was defined as a gross placental examination finding of a blood clot impacting adjacent tissue. Microscopic haemorrhage was defined as ‘high’ (top quintile) scores on an aggregate measure of placental pathology findings suggestive of atypical maternal vessel haemorrhage. These four PH indicators were compared with one another and with risk of PTD assessed by logistic regression analyses. Main outcome measures Preterm delivery and PTD subtypes (i.e. <35 weeks, 35–36 weeks; spontaneous, medically indicated) compared with term deliveries. Results Placental abruption cases had 2.3‐fold to 5.5‐fold increased odds of the other three PH indicators. Disc‐impacting blood clots and microscopic haemorrhage were associated with one another (odds ratio [OR] = 4.6), but not with first‐trimester bleeding. In a multivariable model that included all four PH indicators and confounders, risk of PTD < 35 weeks was elevated with first‐trimester bleeding (OR = 1.9 [1.0, 3.4]), placental abruption (OR = 5.2 [1.7, 16.2]), disc‐impacting blood clots (OR = 2.3 [1.0, 5.0]) and microscopic haemorrhage (OR = 2.4 [1.4, 4.2]). Conclusions Multiple clinical and subclinical PH indicators are associated with PTD, particularly early PTD.

show abstract

“…A female baby was delivered weighing 1565 g (Apgar score: 8 -10, arterial pH: 7.32). Th e histological examination of placenta revealed an increased number of trophoblastic syncytial knots, oft en due to hypertension or uteroplacental insuffi ciency (Tenney -Parker phenomenon) (Benirscke et al 2006). …”

Section: Case Reportmentioning

confidence: 98%

A case of pre-eclampsia and foetal growth restriction after embolisation for a postmolar uterine arteriovenous malformation

Giorgione

Inversetti

Cavoretto

et al. 2015

Journal of Obstetrics and Gynaecology

View full text Add to dashboard Cite

Maternal Diseases Complicating Pregnancy: Diabetes, Tumors, Preeclampsia, Lupus Anticoagulant

Cited by 11 publications

References 521 publications

The defect of both angiogenesis and lymphangiogenesis is involved in preeclampsia

The defect of both angiogenesis and lymphangiogenesis is involved in preeclampsia

Evidence of placental haemorrhage and preterm delivery

A case of pre-eclampsia and foetal growth restriction after embolisation for a postmolar uterine arteriovenous malformation

Contact Info

Product

Resources

About