Maternal deaths with coronavirus disease 2019: a different outcome from low- to middle-resource countries?

Amorim, Melânia Maria Ramos; Takemoto, Maíra Libertad Soligo; Fonseca, Eduardo Borges da

doi:10.1016/j.ajog.2020.04.023

Cited by 68 publications

(65 citation statements)

References 6 publications

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“…Mothers with prior medical conditions may be at higher risk for poor outcomes. In this case, there were several risk factors for preeclampsia such as Somalian origin and high BMI [9].…”

Section: Discussionmentioning

confidence: 78%

Complicated COVID-19 in pregnancy: a case report with severe liver and coagulation dysfunction promptly improved by delivery

Ronnje

Länsberg

Vikhareva

et al. 2020

BMC Pregnancy Childbirth

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Background: It has been proposed that pregnant women and their fetuses may be particularly at risk for poor outcomes due to the coronavirus (COVID-19) pandemic. From the few case series that are available in the literature, women with high risk pregnancies have been associated with higher morbidity. It has been suggested that pregnancy induced immune responses and cardio-vascular changes can exaggerate the course of the COVID-19 infection. Case presentation: A 26-year old Somalian woman (G2P1) presented with a nine-day history of shortness of breath, dry cough, myalgia, nausea, abdominal pain and fever. A nasopharyngeal swab returned positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Her condition rapidly worsened leading to severe liver and coagulation impairment. An emergency Caesarean section was performed at gestational week 32 + 6 after which the patient made a rapid recovery. Severe COVID-19 promptly improved by the termination of the pregnancy or atypical HELLP (Hemolysis, Elevated Liver Enzymes and Low Platelet Count) exacerbated by concomitant COVID-19 infection could not be ruled out. There was no evidence of vertical transmission. Conclusions: This case adds to the growing body of evidence which raises concerns about the possible negative maternal outcomes of COVID-19 infection during pregnancy and advocates for pregnant women to be recognized as a vulnerable group during the current pandemic.

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“…Mothers with prior medical conditions may be at higher risk for poor outcomes. In this case, there were several risk factors for preeclampsia such as Somalian origin and high BMI [9].…”

Section: Discussionmentioning

confidence: 78%

Complicated COVID-19 in pregnancy: a case report with severe liver and coagulation dysfunction promptly improved by delivery

Ronnje

Länsberg

Vikhareva

et al. 2020

BMC Pregnancy Childbirth

View full text Add to dashboard Cite

show abstract

“…Moreover, the physiological changes of pregnancy may impart added risk to patients with COVID‐19. Unfortunately, several associated maternal deaths have been reported to date 2,3 . Furthermore, reports from under‐resourced locations are lacking, and whether reduced access to maternal care may impact maternal mortality is unknown.…”

Section: Characteristic Maternal Survival Maternal Death (N = 301) (Nmentioning

confidence: 99%

Maternal mortality from COVID‐19 in Mexico

Lumbreras‐Marquez

Campos-Zamora

León

et al. 2020

Intl J Gynecology & Obste

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“…3 The first confirmed COVID-19-related maternal death occurred in late March 2020. 4 The number of fatal cases of COVID-19 among pregnant and postpartum women since then have rapidly increased, resulting in a nationwide tragedy. 5 Several aspects about the effects of SARS-CoV-2 infection on the obstetric population remain to be elucidated.…”

Section: Introductionmentioning

confidence: 99%

Risk factors for adverse outcomes among pregnant and postpartum women with acute respiratory distress syndrome due to COVID‐19 in Brazil

Menezes

Takemoto

Nakamura‐Pereira

et al. 2020

Intl J Gynecology & Obste

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Objective: To evaluate whether clinical and social risk factors are associated with negative outcomes for COVID-19 disease among Brazilian pregnant and postpartum women. Methods: A secondary analysis was conducted of the official Acute Respiratory Syndrome Surveillance System database. Pregnant and postpartum women diagnosed with COVID-19 ARDS until July 14, 2020, were included. Adverse outcomes were a composite endpoint of either death, admission to the intensive care unit (ICU), or mechanical ventilation. Risk factors were examined by multiple logistic regression. Results: There were 2475 cases of COVID-19 ARDS. Among them, 23.8% of women had the composite endpoint and 8.2% died. Of those who died, 5.9% were not hospitalized, 39.7% were not admitted to the ICU, 42.6% did not receive mechanical ventilation, and 25.5% did not have access to respiratory support. Multivariate analysis showed that postpartum period, age over 35 years, obesity, diabetes, black ethnicity, living in a peri-urban area, no access to Family Health Strategy, or living more than 100 km from the notification hospital were associated with an increased risk of adverse outcomes. Conclusion: Clinical and social risk factors and barriers to access health care are associated with adverse outcomes among maternal cases of COVID-19 ARDS in Brazil.

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Maternal deaths with coronavirus disease 2019: a different outcome from low- to middle-resource countries?

Cited by 68 publications

References 6 publications

Complicated COVID-19 in pregnancy: a case report with severe liver and coagulation dysfunction promptly improved by delivery

Complicated COVID-19 in pregnancy: a case report with severe liver and coagulation dysfunction promptly improved by delivery

Maternal mortality from COVID‐19 in Mexico

Risk factors for adverse outcomes among pregnant and postpartum women with acute respiratory distress syndrome due to COVID‐19 in Brazil

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