“…In the cohort, breastfeeding reduces the incidence of late lung infections and sepsis and accelerates the initiation of enteral feeding and discharge [84]. The correlation between GM and blood tests suggests a role of Actinobacteria and Proteobacteria in neonatal immune development [67,85,86]. Further studies are needed to confirm these findings and understand the mechanisms involved.…”
Section: Gut Microbiota In F-fed Infantsmentioning
confidence: 98%
“…The development of high-throughput sequencing tools has fundamentally changed our comprehension of the makeup and roles of the GM [61][62][63]. Research has shown that compared to their F-fed peers, breastfed infants have different microbial profiles that are marked by a higher abundance of advantageous commensal bacteria like Bifidobacterium and Lactobacillus, as well as a greater microbial variety [64][65][66][67][68].…”
Section: Gut Microbiota Of Breastfed Infantsmentioning
The gut microbiota (GM) plays a crucial role in human health, particularly during the first years of life. Differences in GM between breastfed and formula (F)-fed infants may influence long-term health outcomes. This systematic review aims to compare the gut microbiota of breastfed infants with that of F-fed infants and to evaluate the clinical implications of these differences. We searched databases on Scopus, Web of Science, and Pubmed with the following keywords: “gut microbiota”, “gut microbiome”, and “neonatal milk”. The inclusion criteria were articles relating to the analysis of the intestinal microbiome of newborns in relation to the type of nutrition, clinical studies or case series, excluding reviews, meta-analyses, animal models, and in vitro studies. The screening phase ended with the selection of 13 publications for this work. Breastfed infants showed higher levels of beneficial bacteria such as Bifidobacterium and Lactobacillus, while F-fed infants had a higher prevalence of potentially pathogenic bacteria, including Clostridium difficile and Enterobacteriaceae. Infant feeding type influences the composition of oral GM significantly. Breastfeeding promotes a healthier and more diverse microbial ecosystem, which may offer protective health benefits. Future research should explore strategies to improve the GM of F-fed infants and understand the long-term health implications.
“…In the cohort, breastfeeding reduces the incidence of late lung infections and sepsis and accelerates the initiation of enteral feeding and discharge [84]. The correlation between GM and blood tests suggests a role of Actinobacteria and Proteobacteria in neonatal immune development [67,85,86]. Further studies are needed to confirm these findings and understand the mechanisms involved.…”
Section: Gut Microbiota In F-fed Infantsmentioning
confidence: 98%
“…The development of high-throughput sequencing tools has fundamentally changed our comprehension of the makeup and roles of the GM [61][62][63]. Research has shown that compared to their F-fed peers, breastfed infants have different microbial profiles that are marked by a higher abundance of advantageous commensal bacteria like Bifidobacterium and Lactobacillus, as well as a greater microbial variety [64][65][66][67][68].…”
Section: Gut Microbiota Of Breastfed Infantsmentioning
The gut microbiota (GM) plays a crucial role in human health, particularly during the first years of life. Differences in GM between breastfed and formula (F)-fed infants may influence long-term health outcomes. This systematic review aims to compare the gut microbiota of breastfed infants with that of F-fed infants and to evaluate the clinical implications of these differences. We searched databases on Scopus, Web of Science, and Pubmed with the following keywords: “gut microbiota”, “gut microbiome”, and “neonatal milk”. The inclusion criteria were articles relating to the analysis of the intestinal microbiome of newborns in relation to the type of nutrition, clinical studies or case series, excluding reviews, meta-analyses, animal models, and in vitro studies. The screening phase ended with the selection of 13 publications for this work. Breastfed infants showed higher levels of beneficial bacteria such as Bifidobacterium and Lactobacillus, while F-fed infants had a higher prevalence of potentially pathogenic bacteria, including Clostridium difficile and Enterobacteriaceae. Infant feeding type influences the composition of oral GM significantly. Breastfeeding promotes a healthier and more diverse microbial ecosystem, which may offer protective health benefits. Future research should explore strategies to improve the GM of F-fed infants and understand the long-term health implications.
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