Maternal Anxiety, Overprotection and Anxious Personality as Risk Factors for Eating Disorder: A Sister Pair Study

Taborelli, Emma; Krug, Isabel; Karwautz, Andreas; Wagner, Gudrun; Haidvogl, M.; Fernández‐Aranda, Fernando; Castro, Rita Tatiana Amiel; Jiménez‐Murcia, Susana; Anderluh, Marija; Collier, David; Treasure, Janet; Micali, Nadia

doi:10.1007/s10608-012-9518-8

Cited by 27 publications

(18 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Adolescent AN showed a distinct pattern of prospective associations compared to other ED, as would be expected from extant literature suggesting an overlap between emotional disorders and AN 39-41 , with some studies showing anxiety onset predating AN and others following onset of AN 42,43 . However, the prospective association of binge/purge-type ED with anxiety disorders is novel and requires replication.…”

Section: Discussionsupporting

confidence: 54%

Adolescent Eating Disorders Predict Psychiatric, High-Risk Behaviors and Weight Outcomes in Young Adulthood

Micali¹,

Solmi²,

Horton³

et al. 2015

Journal of the American Academy of Child & Adolescent Psych

183

219

View full text Add to dashboard Cite

Objective To investigate whether anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), and other specified feeding and eating disorders (OSFED), including purging disorder (PD), subthreshold BN, and BED at ages 14 and 16, are prospectively associated with later depression, anxiety disorders, alcohol and substance use, and self-harm. Method Eating disorders were ascertained at 14 and 16 years of age in 6,140 youth at age 14 (58% of those eligible) and 5,069 at age 16 (52% of those eligible) as part of the prospective Avon Longitudinal Study of Parents and Children (ALSPAC). Outcomes (depression, anxiety disorders, binge drinking, drug use, deliberate self-harm, weight status) were measured using interviews and questionnaires about 2 years following predictors. Generalized estimating equation models adjusting for gender, socio-demographic variables, and prior outcome were used to examine prospective associations between eating disorders and each outcome. Results All eating disorders were predictive of later anxiety disorders. AN, BN, BED, PD, and OSFED were prospectively associated with depression (respectively AN: odds ratio [OR]=1.39 [95% CIs: 1.00-1.94]; BN: OR=3.39[1.25-9.20]; BED: OR=2.00 [1.06-3.75]; PD: OR=2.56 [1.38-4.74]). All eating disorders but AN predicted drug use and deliberate self-harm (BN: OR=5.72[2.22-14.72], PD: OR=4.88[2.78-8.57], subthreshold BN: OR=3.97[1.44-10.98], subthreshold BED: OR=2.32[1.43-3.75]). Whilst BED and BN predicted obesity (respectively OR=3.58 [1.06-12.14] and OR=6.42 [1.69-24.30]), AN was prospectively associated with underweight. Conclusions Adolescent eating disorders, including subthreshold presentations, predict negative outcomes, including mental health disorders, substance use, deliberate self-harm, and weight outcomes. This study highlights the high public health and clinical burden of eating disorders among adolescents.

show abstract

Section: Discussionsupporting

confidence: 54%

Adolescent Eating Disorders Predict Psychiatric, High-Risk Behaviors and Weight Outcomes in Young Adulthood

Micali¹,

Solmi²,

Horton³

et al. 2015

Journal of the American Academy of Child & Adolescent Psych

183

219

View full text Add to dashboard Cite

show abstract

“…A recent sister-pair study [63] revealed that individuals with AN manifested temperamental anxiety including increased harm avoidance, less self-directedness, less reward dependence, more persistence, and lower levels of novelty seeking. Findings from the same study in BN participants revealed increased harm avoidance and less self-directedness as the only significant trait predictors [63], although a recent meta-analysis highlighted greater novelty seeking as unique predictor of BN [62]. Increased harm avoidance and lower self-directedness have also been observed in obese individuals with and without BED, but with less severity than in BN [64].…”

Section: Temperament and Personality-related Ed Risk Factorsmentioning

confidence: 99%

“…Individuals who had more full siblings demonstrated decreased risk, whereas those with more halfsiblings showed higher rates of EDs [86]. With regard to differences between discrete EDs, a sister-pair study of women with AN and BN revealed that participants with AN, but not BN, had mothers with higher maternal anxiety during pregnancy and higher maternal overprotection [63]. In a population-based case-control study of familial aggregation of AN, a family history of affective disorders and sibling history of AN were strong predictors of AN in probands [83•].…”

Section: Family System Factors Implicated In Ed Riskmentioning

confidence: 99%

Recent Advances in Developmental and Risk Factor Research on Eating Disorders

Bakalar

Shank

Vannucci

et al. 2015

Curr Psychiatry Rep

View full text Add to dashboard Cite

The Diagnostic and Statistical Manual of Mental Disorders (i.e., DSM-5) currently recognizes three primary eating disorders: anorexia nervosa, bulimia nervosa, and binge eating disorder. The origins of eating disorders are complex and remain poorly understood. However, emerging research highlights a dimensional approach to understanding the multifactorial etiology of eating disorders as a means to inform assessment, prevention, and treatment efforts. Guided by research published since 2011, this review summarizes recent findings elucidating risk factors for the development of eating disorders across the lifespan in three primary domains: (1) genetic/biological, (2) psychological, and (3) socio-environmental. Prospective empirical research in clinical samples with full-syndrome eating disorders is emphasized with added support from cross-sectional studies, where relevant. The developmental stages of puberty and the transition from adolescence to young adulthood are discussed as crucial periods for the identification and prevention of eating disorders. The importance of continuing to elucidate the mechanisms underlying gene by environmental interactions in eating disorder risk is also discussed. Finally, controversial topics in the field of eating disorder research and the clinical implications of this research are summarized.

show abstract

“…This special section includes two family studies, one using family as a control for genetic influences in order to more closely examine subtle differences in rearing environment (Taborelli et al in press) and the other using the family design to better understand intermediate phenotypes that may demonstrate more robust associations with genetic risk loci (Goddard and Treasure in press). Taborelli et al (in press) examined self-reported shyness, separation anxiety, harm avoidance, and obtained parental reports of prenatal anxiety and earliest age at which children were left with someone else (as an indicator of maternal overprotectiveness) for sibling pairs discordant for an eating disorder. A strength of this design is the use of unaffected sisters as controls in comparison of factors that may uniquely contribute to risk for developing anorexia nervosa or bulimia nervosa.…”

Section: Commentary On Empirical Examinations Of the Association Betwmentioning

confidence: 99%

Commentary on Empirical Examinations of the Association Between Anxiety and Eating Disorders

Keel

2013

Cogn Ther Res

View full text Add to dashboard Cite

A substantial body of research supports comorbidity between eating and anxiety disorders, and articles in this special section explore the nature of this association using severity different research designs. This commentary reviews findings from these articles included, focusing on inferences that may be drawn from each design. Collectively, articles support the need for future studies to examine whether eating and anxiety disorders share underlying mechanisms. If identified, such mechanisms could create opportunities for transdiagnostic interventions that ameliorate suffering from both eating and anxiety disorders

show abstract

Maternal Anxiety, Overprotection and Anxious Personality as Risk Factors for Eating Disorder: A Sister Pair Study

Cited by 27 publications

References 50 publications

Adolescent Eating Disorders Predict Psychiatric, High-Risk Behaviors and Weight Outcomes in Young Adulthood

Adolescent Eating Disorders Predict Psychiatric, High-Risk Behaviors and Weight Outcomes in Young Adulthood

Recent Advances in Developmental and Risk Factor Research on Eating Disorders

Commentary on Empirical Examinations of the Association Between Anxiety and Eating Disorders

Contact Info

Product

Resources

About