Maternal and Perinatal Outcomes of Extreme Obesity in Pregnancy

Crane, Joan; Murphy, Phil; Burrage, Lorraine; Hutchens, Donna

doi:10.1016/s1701-2163(15)30879-3

Cited by 121 publications

(175 citation statements)

References 19 publications

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“…Even among neonates delivered by caesarean section, gestational age remains a stronger predictor of NICU admission than rupture of membranes or trial of labour before delivery (35). Maternal factors found to predict NICU admission in other studies include age, race (16), body mass index (36), premature rupture of membranes, antepartum haemorrhage and medical disorders during pregnancy (32,33). Brown et al suggested that placental ischaemia and endocrine abnormalities associated with these conditions work as biological determinants of preterm birth that act through and with gestational age to produce poor outcomes (34).…”

Section: (%)]mentioning

confidence: 99%

Risk factors for neonatal intensive care unit admission in Amman, Jordan

Sivasubramaniam

Blevins

et al. 2016

East Mediterr Health J

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A better understanding of risk factors for neonatal intensive care unit (NICU) admission can inform interventions to improve neonatal survival. This study aimed to describe a population of newborns admitted to a NICU in Amman, Jordan, and compare them with newborns discharged to home. Newborns born within 96 hours at Al-Bashir Hospital were enrolled from February 2010 to June 2011. Demographic and clinical data were collected for mothers and newborns. Of 5466 enrolled neonates, 373 (6.8%) were admitted to the NICU. The median gestational age of NICU infants was 36 weeks, median birth weight was 2.2 kg and 49.5% were delivered by non-elective caesarean section. Lower gestational age, lower birth weight, delivery by caesarean section and birth in the month of May were statistically significant risk factors for NICU admission. Risk factors for NICU admission were consistent with other populations worldwide; however, median gestational age and birth weight were higher than in developed countries. RÉSUMÉ Une meilleure compréhension des facteurs de risque pour l'admission en unité de soin intensifs néonatals permet d'orienter les interventions en vue d'améliorer la survie des nouveau-nés. La présente étude avait pour objectif de décrire une population de nouveau-nés admis en unité de soins intensifs néonatals à Amman (Jordanie) et de mener une étude comparative avec des nouveau-nés rentrés à domicile. Les nouveau-nés dont la naissance est survenue dans un laps de temps de 96 heures après leur entrée à l'hôpital Al-Bashir ont participé à l'étude entre février 2010 et juin 2011. Des données démographiques et cliniques ont été collectées pour les mères et les nouveau-nés. Sur 5 466 nouveau-nés, 373 (6,8 %) ont été admis en unité de soins intensifs néonatals. L'âge gestationnel médian des enfants admis dans l'unité était de 36 semaines, le poids médian à la naissance était de 2,2 kg et 49,5 % d'entre eux étaient nés par césarienne non élective. Un âge gestationnel plus bas, un poids à la naissance plus faible, une naissance par césarienne et la naissance au cours du mois de mai constituaient des facteurs de risque statistiquement significatifs pour une admission dans l'unité. Ces facteurs de risque coïncidaient avec ceux d'autres populations dans le monde, mais l'âge gestationnel et le poids à la naissance médians étaient plus élevés que dans les pays développés. ‫باألردن‬ ‫ن‬

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Section: (%)]mentioning

confidence: 99%

Risk factors for neonatal intensive care unit admission in Amman, Jordan

Sivasubramaniam

Blevins

et al. 2016

East Mediterr Health J

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“…Lifestyle interventions target established modifiable risk factors including obesity, excessive gestational weight gain and physical inactivity, and encourage ingestion of a high-fibre, low-glycaemic diet. The most effective nutritional preventive strategies for GDM have not been established, but once GDM has been diagnosed there is evidence that focusing on sustainment of low postprandial glucose concentrations is effective in reducing fetal macrosomia [109]. Moderate caloric restriction of one-third of total energy has been shown to improve glucose metabolism without causing ketonaemia in obese women with GDM [110] .…”

Section: Prediction and Prevention Of Gdmmentioning

confidence: 99%

The first trimester: Prediction and prevention of the great obstetrical syndromes

Sweeting

Park

Hyett

2015

Best Practice & Research Clinical Obstetrics & Gynaecol

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“…In view of the persistent increased in maternal obesity in the population, interventions to improve OSA will contribute to decreased the complications brought forth by maternal obesity (23). In a study conducted between 2002 and 2011 on pregnant women with a BMI equal or exceeding 50 Kg/m² (extreme obesity) Crane et al reported increasing maternal deaths as an" outcome of interest" (24). Recently the state of California included BMI in their report of 207 pregnancy related deaths from 2002 to 2005; the paper described different degrees of association between maternal obesity as a contributing factor and the J U S T A C C E P T E D five leading causes of PRD in the state, such as cardiovascular disease, preeclampsia or eclampsia, hemorrhage, venous thromboembolism and amniotic fluid embolism (25).…”

Section: Discussionmentioning

confidence: 99%

Does maternal obesity impact pregnancy-related deaths? Michigan experience

Mariona

2016

The Journal of Maternal-Fetal & Neonatal Medicine

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Obesity is a multifactorial non-communicable condition that has become a public health epidemic worldwide. The Fifth Millennium Development Goal established the goal of a 75% reduction in the maternal mortality ratio (MMR) between 1990 and 2015. Maternal mortality has been difficult to track over time. Obesity affects pregnancy in more than 50% of women of reproductive age in the state of Michigan; the potential impact of maternal obesity and pregnancy-related deaths (PRDs) has not been studied in Michigan. We conducted a secondary analysis of maternal death cases originally reviewed by the Michigan Maternal Mortality Review Committee from 2004 to 2006 seeking to evaluate the impact of maternal obesity on PRD. Two hundred and five maternal deaths occurred during the period of the study, 61 were classified as PRD. The observed occurrence of PRDs in the obese population was 36 cases while in the non-obese was 25 cases. The study showed a 3.7× risk of PRD in the obese parturient.

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Maternal and Perinatal Outcomes of Extreme Obesity in Pregnancy

Cited by 121 publications

References 19 publications

Risk factors for neonatal intensive care unit admission in Amman, Jordan

Risk factors for neonatal intensive care unit admission in Amman, Jordan

The first trimester: Prediction and prevention of the great obstetrical syndromes

Does maternal obesity impact pregnancy-related deaths? Michigan experience

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