Maternal and neonatal factors affecting the incidence of bronchopulmonary dysplasia in very low birth weight newborns

Cunha, Gicelle S.; Filho, Francisco Mezzacappa; Ribeiro, José Dirceu

doi:10.2223/jped.1117

Cited by 9 publications

(11 citation statements)

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“…5,14 As expected, survival without BPD increases with GA. Reaching 32 weeks or more and over-representing infants with growth retardation, mortality increases.…”

Section: Discussionsupporting

confidence: 71%

Displasia broncopulmonar: incidência, fatores de risco e utilização de recursos em uma população sul-americana de recém-nascidos de muito baixo peso

Tapia¹,

Agost²,

Alegria³

et al. 2006

J. Pediatr. (Rio J.)

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Objective: To determine the incidence of bronchopulmonary dysplasia, its risk factors and resource utilization in a large South American population of very low birth weight infants.Methods: Prospectively collected data in infants weighing 500 to 1,500 g born in 16 NEOCOSUR Network centers from 10/2000 through 12/2003. Multivariate relative risk and 95% confidence intervals were estimated by Poisson regression with robust error variance to find factors that affected the risk of bronchopulmonary dysplasia.Results: 1,825 very low birth weight infants survivors were analyzed. Mean birth weight and gestational age were1085±279 g and 29±3 weeks respectively. Bronchopulmonary dysplasia incidence averaged 24.4% and survival without bronchopulmonary dysplasia augmented with increasing gestational age. A higher birth weight and gestational age and a female gender all decreased the risk for bronchopulmonary dysplasia. Factors that independently increased that risk were surfactant requirement, mechanical ventilation, airleak, patent ductus arteriosus, late onset sepsis and necrotizing enterocolitis. Bronchopulmonary dysplasia infants had more days of hospitalization (91±27 vs. 51±19), of mechanical ventilation (19±20 vs. 4±7) and oxygen therapy (72±30 vs. 8±14) in comparison with non BPD infants.Conclusions: Bronchopulmonary dysplasia incidence was 24.4% in a large South American population and is related to greater resource utilization. Population and is related to greater resource utilization. Risk factors for bronchopulmonary dysplasia in this study were: surfactant requirement, mechanical ventilation, airleak, patent ductus arteriosus, late onset sepsis and necrotizing enterocolitis. These studies may provide useful information in the design of effective preventive perinatal strategies.J Pediatr (Rio J). 2006;82(1):15-20: Bronchopulmonary dysplasia, very low birth weight, risk factors, resource utilization, neonates.

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“…5,14 As expected, survival without BPD increases with GA. Reaching 32 weeks or more and over-representing infants with growth retardation, mortality increases.…”

Section: Discussionsupporting

confidence: 71%

Displasia broncopulmonar: incidência, fatores de risco e utilização de recursos em uma população sul-americana de recém-nascidos de muito baixo peso

Tapia¹,

Agost²,

Alegria³

et al. 2006

J. Pediatr. (Rio J.)

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“…A incidência de DBP pode ser comparada à encontrada em estudo semelhante ao relato já apresentado por nossa rede 5,14 .…”

Section: Discussionunclassified

Bronchopulmonary dysplasia: incidence, risk factors and resource utilization in a population of South American very low birth weight infants

Tapia¹,

Agost²,

Alegria³

et al. 2006

J Pediatr (Rio J)

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Bronchopulmonary dysplasia incidence was 24.4% in a large South American population and is related to greater resource utilization. Risk factors for bronchopulmonary dysplasia in this study were: surfactant requirement, mechanical ventilation, airleak, patent ductus arteriosus, late onset sepsis and necrotizing enterocolitis. These studies may provide useful information in the design of effective preventive perinatal strategies.

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“…Chronic lung disease is the most common lung disease among premature newborns with an increasing incidence as birth weight and gestational age decrease [20]. Surfactant has been shown to be beneficial for the prevention and treatment of respiratory distress syndrome [21][22][23][24].…”

Section: Respiratory Drugs and Surfactantmentioning

confidence: 99%

Drug utilisation on a preterm and neonatal intensive care unit in Germany: a prospective, cohort-based analysis

Neubert¹,

Lukas²,

Leis³

et al. 2009

Eur J Clin Pharmacol

129

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Maternal and neonatal factors affecting the incidence of bronchopulmonary dysplasia in very low birth weight newborns

Cited by 9 publications

References 0 publications

Displasia broncopulmonar: incidência, fatores de risco e utilização de recursos em uma população sul-americana de recém-nascidos de muito baixo peso

Displasia broncopulmonar: incidência, fatores de risco e utilização de recursos em uma população sul-americana de recém-nascidos de muito baixo peso

Bronchopulmonary dysplasia: incidence, risk factors and resource utilization in a population of South American very low birth weight infants

Drug utilisation on a preterm and neonatal intensive care unit in Germany: a prospective, cohort-based analysis

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