Materials Nanoarchitectonics for Mechanical Tools in Chemical and Biological Sensing

Abstract

In this Focus Review, nanoarchitectonic approaches for mechanical-action-based chemical and biological sensors are briefly discussed. In particular, recent examples of piezoelectric devices, such as quartz crystal microbalances (QCM and QCM-D) and a membrane-type surface stress sensor (MSS), are introduced. Sensors need well-designed nanostructured sensing materials for the sensitive and selective detection of specific targets. Nanoarchitectonic approaches for sensing materials, such as mesoporous materials, 2D materials, fullerene assemblies, supported lipid bilayers, and layer-by-layer assemblies, are highlighted. Based on these sensing approaches, examples of bioanalytical applications are presented for toxic gas detection, cell membrane interactions, label-free biomolecular assays, anticancer drug evaluation, complement activation-related multiprotein membrane attack complexes, and daily biodiagnosis, which are partially supported by data analysis, such as machine learning and principal component analysis.

Self-assembly as a key player for materials nanoarchitectonics

“…Overall, the nanoarchitectonics concept represents a common standard strategy for materials and system creation in many research fields. Therefore, it has been used in a wide range of research fields and applications including materials production [65][66][67][68], materials fabrication [69,70], materials organization [71][72][73][74], supramolecular assemblies [75][76][77][78], device and physical systems [79,80], sensing [81][82][83][84][85], energy related applications [86][87][88][89][90], environmental strategies [91][92][93][94], and biological and biomedical applications [95][96][97][98][99][100].…”

Tuning the mechanical properties of silicene nanosheet by auxiliary cracks: a molecular dynamics study

“…(I) to (VII) depicts the stress distribution around the crack at various significant strain values. Weak bond created between the atoms adjacent to the tip gets broken at about 5% global strain as shown in (II) and (III).30362 | RSC Adv.,2018,8,[30354][30355][30356][30357][30358][30359][30360][30361][30362][30363][30364][30365] This journal is © The Royal Society of Chemistry 2018RSC Advances Paper Open Access Article. Published on 28 August 2018.…”

Nanoarchitectonics beyond Self‐Assembly: Challenges to Create Bio‐Like Hierarchic Organization

“…Thegenerality of the nanoarchitectonics concept makes it applicable in aw ide range of research fields including materials synthesis, [29] structure fabrication, [30] catalysis, [31] sensing, [32] physical devices, [33] environmental remediation, [34] energy-related applications, [35] biological investigations, [36] and biomedical applications. [37] On the other hand, the nanoarchitectonics strategy substantially differs from conventional macroscopic constructions.I nt he nanoscale regime, structural ambiguities caused by thermal fluctuation and statistical effects cannot be avoided.…”