MATERIAL PROPERTIES OF MMVFs AND THEIR TIME-DEPENDENT FAILURE IN LUNG ENVIRONMENTS

Moore, M.A.; Brown, R. C.; Pigott, G. H.

doi:10.1080/08958370152647645

Cited by 6 publications

(2 citation statements)

References 41 publications

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“…long fibres ''disappear'' or ''clear'' from the lung faster than short ones. Indeed the numbers of short fibres may increase as the long fibres fragment (Moore et al, 2001;Eastes et al, 2007). Since long fibres are those principally responsible for biological activity, the breakage of long fibres represents a considerable reduction in the lung content of hazardous fibres.…”

Section: Principles Of Fibre Toxicity and The Key Role Of Biopersistencementioning

confidence: 99%

“…Fibres having generally lower alumina content and higher boron content have been shown in several in vitro studies to have high biosolubility. The review by Moore et al (2001) details how the structure of glasses is related to the corrosion of fibres in environments typical of the lung, focusing on the properties of MMVFs and their dissolution and corrosionenhanced failure in neutral and acid environments.…”

Section: The Development and Testing Of Less Biopersistent High Tempementioning

confidence: 99%

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Alkaline earth silicate wools – A new generation of high temperature insulation

Brown¹,

Harrison

2012

Regulatory Toxicology and Pharmacology

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Section: Principles Of Fibre Toxicity and The Key Role Of Biopersistencementioning

confidence: 99%

Section: The Development and Testing Of Less Biopersistent High Tempementioning

confidence: 99%

Alkaline earth silicate wools – A new generation of high temperature insulation

Brown¹,

Harrison

2012

Regulatory Toxicology and Pharmacology

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Possible Health Impact of Nanomaterials

Hoet

Brüske‐Hohlfeld²,

Salata

2003

Nanotechnologies for the Life Sciences

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The sections in this article are Introduction Sources of Nanoparticles Epidemiological Evidence Entry Routes into the Human Body Lung Inhalation, Deposition and Pulmonary Clearing of Insoluble Solids Biopersistence of Inhaled Solid Material Systemic Translocation of Inhaled Particles Intestinal Tract Deposition and Translocation Intestinal Translocation and Disease Skin Deposition and Penetration through the Skin Irritation of Skin What Makes Nanoparticles Dangerous? Particle Size – Surface and Body Distribution Effect of Size Effect of Surface Charges Nanoparticles, Thrombosis and Lung Inflammation Prothrombotic Effect Oxidative Stress, Inflammation and Endotoxins Nanoparticles and Cellular Uptake Nanoparticles and the Blood–Brain Barrier Summary and Discussion What Can be Done?

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