Matching of Mechanical Properties of Biological Tissues and Technical Materials for the Fabrication of Anatomical Models by Material Jetting

Preis, Alexander; Riedle, Hannah; Benke, Elisabeth; Franke, Jörg

doi:10.5220/0010384201890194

Cited by 4 publications

(7 citation statements)

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“…One of the major problems affecting the design of trainers with high haptic fidelity is identifying which biomechanical properties are most important to match with synthetic materials. Recently, it has been suggested that hardness and elastic modulus may be the best starting points for the additive manufacturing of trainers 217 . We hoped that the results from this review would provide methodology for measuring elastic moduli and data for the comparison of results; however, this proved to be a more difficult task than anticipated.…”

Section: Discussionmentioning

confidence: 96%

“…Recently, it has been suggested that hardness and elastic modulus may be the best starting points for the additive manufacturing of trainers. 217 We hoped that the results from this review would provide methodology for measuring elastic moduli and data for the comparison of results; however, this proved to be a more difficult task than anticipated.…”

Section: Concept: Biomechanical Propertiesmentioning

confidence: 99%

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Applied use of biomechanical measurements from human tissues for the development of medical skills trainers: a scoping review

Kriener,

Whiting,

Storr

et al. 2023

JBI Evidence Synthesis

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Objective: The objective of this review was to identify quantitative biomechanical measurements of human tissues, the methods for obtaining these measurements, and the primary motivations for conducting biomechanical research. Introduction: Medical skills trainers are a safe and useful tool for clinicians to use when learning or practicing medical procedures. The haptic fidelity of these devices is often poor, which may be because the synthetic materials chosen for these devices do not have the same mechanical properties as human tissues. This review investigates a heterogenous body of literature to identify which biomechanical properties are available for human tissues, the methods for obtaining these values, and the primary motivations behind conducting biomechanical tests. Inclusion criteria: Studies containing quantitative measurements of the biomechanical properties of human tissues were included. Studies that primarily focused on dynamic and fluid mechanical properties were excluded. Additionally, studies only containing animal, in silico, or synthetic materials were excluded from this review. Methods: This scoping review followed the JBI methodology for scoping reviews and the Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for Scoping Reviews (PRISMA-ScR). Sources of evidence were extracted from CINAHL (EBSCO), IEEE Xplore, MEDLINE (PubMed), Scopus, and engineering conference proceedings. The search was limited to the English language. Two independent reviewers screened titles and abstracts as well as full-text reviews. Any conflicts that arose during screening and full-text review were mediated by a third reviewer. Data extraction was conducted by 2 independent reviewers and discrepancies were mediated through discussion. The results are presented in tabular, figure, and narrative formats. Results: Data were extracted from a total of 186 full-text publications. All of the studies, except for 1, were experimental. Included studies came from 33 different countries, with the majority of the studies coming from the United States. Human tissues samples were ex vivo, and the most commonly studied tissue type was musculoskeletal. In this study, nearly 200 unique biomechanical values were reported, and the most commonly reported value was Young’s (elastic) modulus. The most common type of mechanical test performed was tensile testing, and the most common reason for testing human tissues was to characterize biomechanical properties. Although the number of published studies on biomechanical properties of human tissues has increased over the past 20 years, there are many gaps in the literature. Of the 186 included studies, only 7 used human tissues for the design or validation of medical skills training devices. Furthermore, in studies where biomechanical values for human tissues have been obtained, a lack of standardization in engineering assumptions, methodologies, and tissue preparation may implicate the usefulness of these values. Conclusions: This review is the first of its kind to give a broad overview of the biomechanics of human tissues in the published literature. With respect to high-fidelity haptics, there is a large gap in the published literature. Even in instances where biomechanical values are available, comparing or using these values is difficult. This is likely due to the lack of standardization in engineering assumptions, testing methodology, and reporting of the results. It is recommended that journals and/or experts in engineering fields conduct further research to investigate the feasibility of implementing reporting standards. Review Registration: Open Science Framework osf.io/fgb34

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Section: Discussionmentioning

confidence: 96%

Section: Concept: Biomechanical Propertiesmentioning

confidence: 99%

Applied use of biomechanical measurements from human tissues for the development of medical skills trainers: a scoping review

Kriener,

Whiting,

Storr

et al. 2023

JBI Evidence Synthesis

View full text Add to dashboard Cite

show abstract

“…Since the goal of this research was to select synthetic materials that match tissue properties, tissues were not pre-conditioned [4]. The cross-head speed was selected based on similar work [3] and was conducted at a quasi-static rate of 5 mm/min.…”

Section: Tensile Testingmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…It is presumed that by choosing synthetic materials with the same or similar properties to human tissues, a trainer with high haptic fidelity can be designed [3][4][5]. Whilst there is a myriad of mechanical properties to choose from, it is theorized that tensile properties may be the best starting point [4]. There is a body of literature that contains some tensile properties of the abdominal wall; however, most of the studies are concerned with hernia repair.…”

Section: Introductionmentioning

confidence: 99%

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Mechanical Characterization of the Human Abdominal Wall Using Uniaxial Tensile Testing

Kriener,

Lala,

Homes

et al. 2023

Bioengineering

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It is generally accepted that the human abdominal wall comprises skin, subcutaneous tissues, muscles and their aponeuroses, and the parietal peritoneum. Understanding these layers and their mechanical properties provides valuable information to those designing procedural skills trainers, supporting surgical procedures (hernia repair), and engineering-based work (in silico simulation). However, there is little literature available on the mechanical properties of the abdominal wall in layers or as a composite in the context of designing a procedural skills trainer. This work characterizes the tensile properties of the human abdominal wall by layer and as a partial composite. Tissues were collected from fresh-never-frozen and fresh-frozen cadavers and tested in uniaxial tension at a rate of 5 mm/min until failure. Stress–strain curves were created for each sample, and the values for elastic moduli, ultimate tensile strength, and strain at failure were obtained. The experimental outcomes from this study demonstrated variations in tensile properties within and between tissues. The data also suggest that the tensile properties of composite abdominal walls are not additive. Ultimately, this body of work contributes to a deeper comprehension of these mechanical properties and will serve to enhance patient care, refine surgical interventions, and assist with more sophisticated engineering solutions.

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Mechanical Characterization of the Human Abdominal Wall Using Uniaxial Tensile Testing

Kriener,

Lala,

Homes

et al. 2023

Preprint

View full text Add to dashboard Cite

It is generally accepted that the human abdominal wall is comprised of skin, subcutaneous tissues, muscles and their aponeuroses, and the parietal peritoneum. Understanding these layers and their mechanical properties provides valuable information to those designing procedural skills trainers, supporting surgical procedures (hernia repair), and engineering-based work (in silico simulation). However, there is little literature available on the mechanical properties of the abdominal wall in layers or as a composite. This work characterizes the tensile properties of the human abdominal wall by layer and as a partial composite. Tissues were collected from fresh-never-frozen and fresh-frozen cadavers and tested in uniaxial tension at a rate of 5 mm/min until failure. Stress-strain curves were created for each sample, and the values for elastic moduli, ultimate tensile strength, and strain at failure were obtained. The experimental outcomes from this study demonstrated variation of tensile properties within and between tissues. The data also suggest that the tensile properties of composite abdominal walls are not additive. Ultimately, this body of work contributes to a deeper comprehension of these mechanical properties and will serve to enhance patient care, refine surgical interventions, and assist with more sophisticated engineering solutions.

show abstract

Matching of Mechanical Properties of Biological Tissues and Technical Materials for the Fabrication of Anatomical Models by Material Jetting

Cited by 4 publications

References 0 publications

Applied use of biomechanical measurements from human tissues for the development of medical skills trainers: a scoping review

Applied use of biomechanical measurements from human tissues for the development of medical skills trainers: a scoping review

Mechanical Characterization of the Human Abdominal Wall Using Uniaxial Tensile Testing

Mechanical Characterization of the Human Abdominal Wall Using Uniaxial Tensile Testing

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