2021
DOI: 10.1002/lio2.672
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Mastoid obliteration and external auditory canal reconstruction with silicone block in canal wall down mastoidectomy

Abstract: Objective: To prevent cavity problems in canal wall down mastoidectomy, silicone block for mastoid obliteration was used. Methods:In this retrospective cohort study, 39 patients (21 males and 18 females) underwent canal wall down mastoidectomy and mastoid obliteration using silicone block. We evaluated the postoperative outcome, the time until epithelialization of the cavity, graft success rate, and the hearing outcome. Results:The time until complete epithelialization of the mastoid cavity was 35.5 ± 5.4 days… Show more

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“…The pore size and intercommunication of scaffolds are other important factors affecting their biological properties, such as promoting the migration and proliferation of cells, facilitating the infiltration of blood vessels, improving the local nutritional and metabolic environment, and accelerating the process of bone repair [ [16] , [17] , [18] ]. Considering the influence of the size of the new blood vessels and the diameter of the new bone Haver's canal, the academic community generally believes that a minimum pore diameter of <100 μm is unfavorable for the ingrowth of blood vessels and the formation of new bone [ 19 , 20 ]. The transverse and longitudinal meridians of the S53P4/PCL scaffolds fabricated in this study were all >100 μm, the fibers inside the scaffolds were well organized, and the pores of each layer were interconnected, which was fully beneficial to cell migration, blood vessel growth, and new bone formation.…”
Section: Discussionmentioning
confidence: 99%
“…The pore size and intercommunication of scaffolds are other important factors affecting their biological properties, such as promoting the migration and proliferation of cells, facilitating the infiltration of blood vessels, improving the local nutritional and metabolic environment, and accelerating the process of bone repair [ [16] , [17] , [18] ]. Considering the influence of the size of the new blood vessels and the diameter of the new bone Haver's canal, the academic community generally believes that a minimum pore diameter of <100 μm is unfavorable for the ingrowth of blood vessels and the formation of new bone [ 19 , 20 ]. The transverse and longitudinal meridians of the S53P4/PCL scaffolds fabricated in this study were all >100 μm, the fibers inside the scaffolds were well organized, and the pores of each layer were interconnected, which was fully beneficial to cell migration, blood vessel growth, and new bone formation.…”
Section: Discussionmentioning
confidence: 99%