Mastitis effects on reproductive performance in dairy cattle: a review

Kumar, Naveen; Manimaran, A.; Kumaresan, A.; Jeyakumar, Sakthivel; Sreela, L.; Mooventhan, P.; Sivaram, M.

doi:10.1007/s11250-017-1253-4

Cited by 49 publications

(32 citation statements)

References 76 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The majority of studies in cattle looking at infection and reproductive performance have utilized dairy cattle and focused on the common postpartum complication mastitis 31 . A potential mechanism and link between inflammation and infertility in cattle has been proposed by Hansen et al .…”

Section: Discussionmentioning

confidence: 99%

Plasma metabolomic profiles differ at the time of artificial insemination based on pregnancy outcome, in Bos taurus beef heifers

Phillips

Read

Kriese-Anderson

et al. 2018

Sci Rep

View full text Add to dashboard Cite

Infertility remains the most prevalent reason for cattle being removed from production environments. We utilized metabolomic profiling to identify metabolites in the blood plasma that may be useful in identifying infertile heifers at the time of artificial insemination (AI). Prior to AI, phenotypic parameters including body condition, weight, and reproductive organ measurements were collected. These were determined not effective at differentiating between fertile and infertile heifers. Analysis of the resulting metabolomic profiles revealed 15 metabolites at significantly different levels (T-test P ≤ 0.05), with seven metabolites having a greater than 2-fold difference (T-test P ≤ 0.05, fold change ≥2, ROC-AUC ≥ 0.80) between infertile and fertile heifers. We further characterized the utility of using the levels of these metabolites in the blood plasma to discriminate between fertile and infertile heifers. Finally, we investigated the potential role inflammation may play by comparing the expression of inflammatory cytokines in the white blood cells of infertile heifers to that of fertile heifers. We found significantly higher expression in infertile heifers of the proinflammatory markers tumor necrosis factor alpha (TNFα), interleukin 6 (IL6), and the C-X-C motif chemokine 5 (CXCL5). Our work offers potentially valuable information regarding the diagnosis of fertility problems in heifers undergoing AI.

show abstract

Section: Discussionmentioning

confidence: 99%

Plasma metabolomic profiles differ at the time of artificial insemination based on pregnancy outcome, in Bos taurus beef heifers

Phillips

Read

Kriese-Anderson

et al. 2018

Sci Rep

View full text Add to dashboard Cite

show abstract

“…Beyond its negative impact on milk yield and milk components, mastitis has a detrimental effect on reproductive performance in dairy cows [ 7 - 11 ].…”

Section: Introductionmentioning

confidence: 99%

Milk amyloid A as a biomarker for diagnosis of subclinical mastitis in cattle

Hussein¹,

El-Razik²,

Gomaa³

et al. 2018

Vet World

View full text Add to dashboard Cite

Background and Aim:Mastitis is one of the most vital noteworthy monetary risks to dairy ranchers and affects reproductive performance in dairy cattle. However, subclinical mastitis (SCM) negatively affects milk quality and quantity and associated with economic losses as clinical mastitis. It is recognizable only by additional testing. Somatic cell count (SCC) is currently used worldwide for the screening of intramammary infection (IMI) infections. However, somatic cells (SC) are affected by numerous factors and not always correlate with infection of the udder. Therefore, the aim of the present study was to evaluate the milk amyloid A (MAA) in the milk of normal and SCM cows and compare the sensitivity of both MAA secretion and SCC in response to mammary gland bacterial infection.Materials and Methods:A total of 272 quarter milk samples collected from 68 Friesian cows after clinical examination for detection of clinical mastitis were employed in this study. All quarter milk samples (272) were subjected to bacteriological examination, while SCs were assessed in samples (220). Following SCC estimation and bacteriological examination, the apparently normal quarter milk samples were categorized into 7 groups and MAA concentration was estimated in normal and subclinical mastitic milk samples.Results:Prevalence of clinical mastitis was 19.12 % (52 quarters), while 80.88 % (220 quarters) were clinically healthy with normal milk secretion. Of those 220 clinically healthy quarter milk samples, 72 (32.73%) showed SCM as detected by SCC (SCC ≥500,000 cells/ml). The most prevalent bacteria detected in this study were streptococci (48.53%), Staphylococcus aureus (29.41%), Escherichia coli (36.76%), and coagulase-negative staphylococci (11.76%). Results of MAA estimation revealed a strong correlation between MAA secretion level and SCC in agreement with the bacteriological examination. Interestingly, there was a prompt increase in MAA concentration in Group III (G III) (group of milk samples had SCC ≤200,000 cells/ml and bacteriologically positive) than Group I (G I) (group of milk samples with SCC ≤500,000 cells/ml and bacteriologically negative), as MAA concentration in G III was about 4 times its concentration in G I.Conclusion:Our study provides a strong evidence for the significance of MAA measurement in milk during SCM, and MAA is more sensitive to IMI than SCC. This can be attributed to rapid and sensitive marker of inflammation. The advantage of MAA over other diagnostic markers of SCM is attributed the minute or even undetectable level of MAA in the milk of healthy animals, it is not influenced by factors other than mastitis, and could be estimated in preserved samples. Therefore, we recommend that estimation of MAA concentration in milk is a more useful diagnostic tool than SCC to detect SCM and to monitor the udder health in dairy cattle.

show abstract

“…For example, mastitis infection can cause endotoxin release, immune system activation, cytokine production, and body temperature elevation. The cumulative effects on the whole animal can damage the developing embryo and (or) cause regression of the corpus luteum and early embryonic loss (Hansen et al, 2004;Kumar et al, 2017).…”

Section: Elevated Body Temperature Systemic Toxicity With Fever Andmentioning

confidence: 99%

Stress, strain, and pregnancy outcome in postpartum cows

Lucy

2019

Anim Reprod

View full text Add to dashboard Cite

Stress affects the productivity and fertility of cattle. Stress causes strain and individual animals experience different amounts of strain in response to the same amount of stress. The amount of strain determines the impact of stress on fertility. Typical stresses experienced by cattle include environmental, disease, production, nutritional, and psychological. The effect of stress on the reproductive system is mediated by body temperature (heat stress), energy metabolites and metabolic hormones (production and nutritional stresses), the functionality of the hypothalamus-pituitary-gonadal (HPG) axis and (or) the activation of the hypothalamuspituitary-adrenal (HPA) axis. The strain that occurs in response to stress affects uterine health, oocyte quality, ovarian function, and the developmental capacity of the conceptus. Cows that have less strain in response to a given stress will be more fertile. The goal for future management and genetic selection in farm animals is to reduce production stress, manage the remaining strain, and genetically select cattle with minimal strain in response to stress.

show abstract

Mastitis effects on reproductive performance in dairy cattle: a review

Cited by 49 publications

References 76 publications

Plasma metabolomic profiles differ at the time of artificial insemination based on pregnancy outcome, in Bos taurus beef heifers

Plasma metabolomic profiles differ at the time of artificial insemination based on pregnancy outcome, in Bos taurus beef heifers

Milk amyloid A as a biomarker for diagnosis of subclinical mastitis in cattle

Stress, strain, and pregnancy outcome in postpartum cows

Contact Info

Product

Resources

About