Masterclass series in peripheral arterial disease

Olin, Jeffrey W.

doi:10.1191/1358863x05vm591xx

Cited by 31 publications

(5 citation statements)

References 54 publications

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“…No patients with TAO had any form of myocardial episode. These findings correlate with another studies [24,[26][27][28] .…”

Section: Discussionsupporting

confidence: 93%

Study of clinical profile of peripheral vascular disease in department of surgery

Jaykar,

Deshmukh,

Sawant

et al. 2023

Int. J. Surg. Sci.

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Peripheral vascular disease is circulation disorders that affect blood vessels outside of the heart and brain. Smoking tobacco is the main culprit for PVD. Management of atherosclerosis plays an important role in adult medical care. The objective of present study was to determine cardiovascular comorbidities associated with different stages of peripheral vascular disease and current use of pharmacological cardiovascular risk reducing therapy among men and women with the disease. This study was conducted by random selection of 60 cases with Peripheral Arterial disease of the lower extremities admitted to surgical wards of our tertiary care Centre done during the period from August 2020 to August 2022. The present study of chronic lower limb ischemia. TAO and Atherosclerosis are the etiologies for ischemia in these cases, with atherosclerosis being more common of the two. TAO presented at a younger age group whereas atherosclerosis presented in the older age group.

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“…No patients with TAO had any form of myocardial episode. These findings correlate with another studies [24,[26][27][28] .…”

Section: Discussionsupporting

confidence: 93%

Study of clinical profile of peripheral vascular disease in department of surgery

Jaykar,

Deshmukh,

Sawant

et al. 2023

Int. J. Surg. Sci.

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“…The ABI was measured based on previously established methods 24–26 . Blood pressure cuffs were placed on each brachial artery and above each malleolus.…”

Section: Methodsmentioning

confidence: 99%

Peripheral Arterial Disease in African Americans: Clinical Characteristics, Leg Symptoms, and Lower Extremity Functioning

Rucker-Whitaker

Greenland

Liu

et al. 2004

J American Geriatrics Society

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“…PAD also tends to progress faster and lead to worse outcomes in T2DM patients (8,9). Several risk factors for PAD have been established, including age, race, smoking, hypertension, and lipids (10–13). There is also evidence that biomarkers indicative of inflammation and/or coagulation, such as C-reactive protein (CRP), d -dimer, and fibrinogen, may be associated with increased PAD risk and/or worse outcomes (14–21).…”

Section: Introductionmentioning

confidence: 99%

Risk Factors for Incident Peripheral Arterial Disease in Type 2 Diabetes: Results From the Bypass Angioplasty Revascularization Investigation in Type 2 Diabetes (BARI 2D) Trial

et al. 2014

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OBJECTIVEThe aim of this article was to define risk factors for incidence of peripheral arterial disease (PAD) in a large cohort of patients with type 2 diabetes mellitus (T2DM), overall and within the context of differing glycemic control strategies.RESEARCH DESIGN AND METHODSThe Bypass Angioplasty Revascularization Investigation in Type 2 Diabetes (BARI 2D) randomized controlled trial assigned participants to insulin-sensitizing (IS) therapy versus insulin-providing (IP) therapy. A total of 1,479 participants with normal ankle-brachial index (ABI) at study entry were eligible for analysis. PAD outcomes included new ABI ≤0.9 with decrease at least 0.1 from baseline, lower extremity revascularization, or lower extremity amputation. Baseline risk factors within the overall cohort and time-varying risk factors within each assigned glycemic control arm were assessed using Cox proportional hazards models.RESULTSDuring an average 4.6 years of follow-up, 303 participants (20.5%) experienced an incident case of PAD. Age, sex, race, and baseline smoking status were all significantly associated with incident PAD in the BARI 2D cohort. Additional baseline risk factors included pulse pressure, HbA1c, and albumin-to-creatinine ratio (P < 0.05 for each). In stratified analyses of time-varying covariates, changes in BMI, LDL, HDL, systolic blood pressure, and pulse pressure were most predictive among IS patients, while change in HbA1c was most predictive among IP patients.CONCLUSIONSAmong patients with T2DM, traditional cardiovascular risk factors were the main predictors of incident PAD cases. Stratified analyses showed different risk factors were predictive for patients treated with IS medications versus those treated with IP medications.

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Masterclass series in peripheral arterial disease

Cited by 31 publications

References 54 publications

Study of clinical profile of peripheral vascular disease in department of surgery

Study of clinical profile of peripheral vascular disease in department of surgery

Peripheral Arterial Disease in African Americans: Clinical Characteristics, Leg Symptoms, and Lower Extremity Functioning

Risk Factors for Incident Peripheral Arterial Disease in Type 2 Diabetes: Results From the Bypass Angioplasty Revascularization Investigation in Type 2 Diabetes (BARI 2D) Trial

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