Mast Cell Leukemia: Review of a Rare Disease and Case Report of Prolonged Survival after Allogeneic Stem Cell Transplant

An autopsy case of mast cell leukemia

“…2 It is stated that the diagnosis of MCL should be made on the bone marrow aspirate rather than biopsy or autopsy to evaluate the percentage of mast cells in bone marrow. 4 In this case, the autopsy was performed to evaluate the cause of the rapid progression of anemia, DIC, and hemorrhage of unknown origin. We considered that severe anemia and bleeding tendency resulted from the SM.…”

“…The aleukemic variant (the definition of which differs only in that the mast cells account for <10% of peripheral blood white cells) is more common . It is stated that the diagnosis of MCL should be made on the bone marrow aspirate rather than biopsy or autopsy to evaluate the percentage of mast cells in bone marrow …”