Masson’s tumor involving the hand: A case report

The Vascular Convolutions-Papillary Endothelial Hyperplasia

“…The tumour is described as an endothelial cell neoplasm inducing vascular obstruction and tissue necrosis wherein reactive mechanisms of the lesion appear subsequent to thrombus organization and endothelial restoration. Hyperaemia and lymph stasis along with on site production of angiogenic growth factors are implicated in the genesis of the neoplasm [3]. On account of complex clinical representation, essentially benign papillary endothelial hyperplasia requires segregation from malignant vascular lesions, in order to circumvent misinterpretation and aggressive therapy as demolition surgery or regional irradiation.…”

“…Cogent determination of papillary endothelial hyperplasia is challenging on account of clinical and radiographic semblance to diverse vascular tumours, especially angiosarcoma. Also, infrequently discerned recurrent papillary endothelial hyperplasia mandates a distinction from angiosarcoma [3,4].…”

“…A predilection for head and neck, trunk, extremities, fingers or hand is denominated, although uncharted neoplastic presence is documented upon eyelid, orbit, masseters, nasal sinuses, parotid gland, mandible, pharynx, thyroid, oral cavity, sino-nasal cavity, foot and renal parenchyma. Spinal cord, skull and base of skull are sites of skeletal involvement [3,4].…”

“…Although exceptional, intraoral sites implicated in decreasing order of frequency, are lower lip, tongue, buccal mucosa and upper lip. Papillary endothelial hyperplasia is rare within intra-cranial location wherein a malignant neoplasm is recapitulated [3,4].…”

“…Of obscure pathogenesis, several mechanisms are proposed for genesis of papillary endothelial hyperplasia a) An intravascular endothelial cell proliferation ensues with concomitant configuration of papillary architecture which can progress to necrosis and cellular degeneration [3,4].…”