“…Although anticoagulation may reduce morbidity and mortality for people with cavernous sinus thrombosis, its role for treating superior ophthalmic vein thrombosis is less clear. In our review, 7 cases received anticoagulation, with 1 fatal outcome attributed to a retroperitoneal bleed [15] while 6 other case reports described anticoagulation including with heparin, low–molecular weight heparin, and aspirin without sequelae [11, 12, 14, 16, 17, 20]. The decision to start anticoagulation for individuals with septic superior ophthalmic vein thrombosis is still best considered on a case-by-case basis, taking into account age, comorbid conditions, response to antibiotic therapy, and whether invasive procedures were performed.…”